OSD3 drugs

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emm64
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OSD3 drugs
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2013-05-03 01:45:08
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OSD3 drugs
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OSD3 drugs
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  1. atorvastatin
    • lipitor;
    • antilipemic agent, HMG COA reductase inhibitor;
    • tx of dyslipidemia or primary prevention of CV disease;
    • no LA, dental, bleeding precautions;
  2. metformin
    • antidiabetic agent, biguanide
    • tx of DM type II
    • can cause taste disorders, AM appt  to avoid stress induced hypoglycemia
  3. glipizide
    • antidiabetic agent, sulfonylurea
    • mangment of type II diabetes
    • stimulates glucose release from pancreatic beta celles
    • LA/Vaso- no contra;
    • effects on dental tx- AM appt to avoid stress induced hypoglycemia;
  4. atenolol
    • antianginal agent, beta blocker (beta-1 selecive)
    • tx of htn, angina pectoris, post MI
    •  no effects on bleeding, dental, LA/vaso
  5. hydrochlorothiazide
    • diuretic, thiazide;
    • management of mild to moderate HTN, tx of edema in heart failure nrphrotic syndrome;
    • LA/vaso- no contra;
    • can casue orthostatic hypotension and hypotension
    • ; no bleeding conra;
    • inhibits Na reabsortion in the distal tubules
  6. lisinoprol
    • ACE inhibitor;
    • tx of HTN;
    • afterload reduction in heart failure;
    • no LA/Vaso, bleeding, dental precautions;
  7. venlafaxine
    • antidepressant, serotonin/ NE reuptake inhibitor;
    • tx of major depressive disorder, generalized anxiety disorder, social anxiety, panic disorder;
    • can block NE reuptake with CNS synapse;
    • significant xerostomia;
    • may impair platelet aggregation resulting in
    • bleeding
  8. ticagrelor
    • antiplatelet agent,  cyclopentylthriazolopyrimidine;
    • secondary prevention of thrombotic events in pts;
    • no LA/Vaso, dental tx precautions;
    • can lead to major or minor bleeding issues;
  9. timolol eye drop
    • beta blocker, nonselevtive; antiglaucoma; tx of elevated intraocular
    • pressure; epi can interact with nonselective beta blockers
    • can cause xerostomia;
    • can
    • enhance pressor response to epi;
  10. Metoprolol
    • • Category= antiangina agent, beta blocker, beta-1 selective; tx of angina pectoris, HTN, or hemodynamically acute MI;
    • no local anesthetic or vasoconstrictor precautions; effects on dental Tx: cardioselective beta blocker.
    • Local anesthetic with vasocontrcitor can be safely used.
    • Nonselective beta blockers enhance the pressor response to epi, resulting in HTN and bradycardia (not reported for Metoprolol). Long term NSAID used can reduce the hypotensive effect of beta-blockers.
  11. levothyroxine
    • replacement or supplemental therapy in hypothyroidism
    • pituitary TSH suppression;
    • no precautions with LA/vaso if pt is well controlled with levothyroxine
    • no significant effects on dental tx
    • no specific effects on bleeding;
    • pregnancy risk category “A”,
    • no risks- minimally cross the placenta; enters breast milk, use caution, but are minimal and needed for normal lactation, do not discontinue normal does
    • can cause angina
  12. furosemide
    • “lasix”
    • diuretic, loop; manangment of edema with hear failure and hepatic and renal disease, acute pulmonary edema, and tx of HTN;
    • LA/vaso considerations=none;
    • no significant effects on dental tx;
    • no effect on bleeding;
    • inhibits reabsorption of Na and Cl in the ascending loop of henle and distal renal tubule, interfering with
    • the cl binding cotransport system thus causing increased excretion of H20, Na, Cl, Mg, Ca
    • pregnancy category “C”- crosses the placenta, can increase birth weight
    • enters break milk, use caution, may suppress lactation
  13. albuterol inhaler
    • o beta 2 agoinist; tx or prevention of bronchospasm in pts with reversible obstructive
    • airway disease; LA/Vaso- none; dental tx considerations: xerostomia;
    • no effect on bleeding;
    • may increase the levels/effects of loop diuretics;
    • pregnancy class “C”-
    • crosses the placenta, tocolytic effects, fetal tachycardia, fetal hypoglycemia but can
    • be used safely during pregnancy;
  14. Mycophenolate mofetil-
    • immunosuppressant
    • prohpyalixis of organ rejection concomitanly with cyclosporines and corticosteroids
    • LA/Vaso no contra;
    • dental- mouth ulceration, gum hyperplasia, gingivitis, dry mouth, dysphagia, oral candidiais, stomatitis
  15. Presnisone-
    • corticosteroid;
    • tx of allergies, inflammatory diseases, or autoimmune diseases
    • no contra
  16. Tacrolimus
    • calcineurin inhibitor, immunosuppressant;
    • prevention of organ rejection;
    • stomatitis, oral candidiasis, dysphagia, esophagitis;
    • thrombocytopenia and delayed coagulation; calcineurin is a protein phosphatase that activates T cells
  17. Insulin
    • (novolog 5 U AM, Lantus 10 U AM, NPH 4 U PM)
    • a. Novalog- insulin aspart; rapid acting;
    • b. Lantus- insulin glargine; long acting
    • c. NPH- intermediate acting
  18. Metoprolol
    • antiagina agent, beta blocker, beta-1 selective;
    • tx of angina pectoris, HTN;
    • LA with vaso can be safely used;
    • NON selective enhance pressor function;
  19. Azithromycin-
    • macrolide AB;
    • alternate oral AB for prevention of IE in individuals allergic to penicillin;
    • targets aerobic G+ cocci and some anaerobes;
  20. Atovaquone-
    • antiprotozoal;
    • tx and prophylaxis of acute mild to moderate Pneumocysits jirovecci prneumonia;
    • can cause oral moniliasis (oral candidiasis);
    • no LA/vaso/bleeding effects
  21. Voriconazole
    • antifungal;
    • prolongs QT interval and has a risk of causing torsade de pointes;
    • consult with physian before delivieng epi;
    • can cause xerostomia
  22. Pantoprazole
    • proton pump inhibitor;
    • tx and maintentance of GERD;
    • no contra
  23. Fenofibrate
    • antilipemic, fibric acid;
    • tx of elevated triglyceride levels, reduction of LDL, total cholesterol;
    • can cause dry mouth and tooth disorder
    • implicated in causing thrombocytopaenia
  24. Alendronate-
    • bisphosphonate derivative;
    • tx and prevention of osteoporosis, Paget’s Disease of the bone in patients with alkaline phos. 2x higher than normal,
    • tx of glucorcorticoid induced osteoporosis in patients receiving corticosteroids
    • LA/ vaso considerations- none
    • dental effects-osteonecrosis of the jaw, delayed healing
    • no bleeding precautions
    • inhibits osteoclasts;
  25. Albuterol inhaler
    • beta 2 agoinist;
    • tx or prevention of bronchospasm in pts with reversible obstructive airway disease;
    • LA/Vaso- none;
    • dental tx considerations: xerostomia;
    • no effect on bleeding;
    • may increase the levels/effects of loop diuretics
  26. Baby ASA
    • antiplatelet agent, salicylate;
    • can be used for post operative pain, inflammation, and fever, prevention and tx of MI, acute ischemic stroke,
    • irreversibly inhibits platelet aggregation-
    • returns to normal in 7-10 days after discontiniuation;
  27. Magnesium
    • correction of hypomagnesium;
    • may prevent GI absorption of tetercycline;
    • cofactor in many enzymatic reactions in protein synthesis and carb metabolism
  28. Fish oil
    lowers risk of coronary artery disease and decrease serum triglycerides
  29. taste
    metformin: biguanide (DM II)
  30. xero
    • venlafaxine: antidepressant, SSRI, NE reup inhib, significant xerostomia, platelet agg
    • timolol: nonselective B-blocker, enhance pressor response(HTN, brady)
    • albuterol
    • mycophenolate mofetil: reversible inhibitor of inosine monophosphate dehydrogenase[1] (IMPDH), mouth ulceration, gum hyperplasia, gingivitis, dry mouth, dysphagia, oral candidiais, stomatitis
    • voricanazole: antifungal
  31. BRONJ
    alendronate: bisphosphonate
  32. AM appt
    • metformin: biguanide
    • glipizide: sulfonylurea
  33. bleeding
    • venlafaxine: antidepressant, SSRI, NE reup inhib, significant xerostomia, platelet agg
    • ticagrelor: antiplatelet
    • baby ASA
  34. orthostatic
    hydrochlorothiazide: loop diuretic
  35. stomatitis, oral candidiasis, dysphagia, esophagitis
    • tacrolimus: calcineurin inhibitor, immunosuppressant
    • mycophenolate mofetil:reversible inhibitor of inosine monophosphate dehydrogenase[1] (IMPDH), mouth ulceration, gum hyperplasia, gingivitis, dry mouth, dysphagia, oral candidiais, stomatitis
  36. oral moniliasis
    atovaquone: anti-protozoal
  37. dry mouth and tooth disorder
    fenofibrate: antilipemic

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