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BIOL 404-Exam 4-GI 6
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How much fat do Americans eat daily?
25-160 grams
What forms of fats do people eat?
Triacylglycerides
What is a Triacylglyceride?
3 Fatty acids bound to glycerol
What is the basic process of fat emulsification?
Small Fat globules are coated with Bile and phospholipids
Where does triglyceride digestion occur?
Mostly in the small intestine
What is the major digestion enzyme for Fat?
Pancreatic lipase
Describe the action of pancreatic lipase:
Water soluble and acts on the surface of Triglycerides
What is the solubility of pancreatic lipase?
Water soluble
What needs to occur for aggregated fat droplets to be efficiently digested?
They need to be broken into smaller droplets, called emulsion droplets
Why are emulsion droplets more efficiently digested?
They have a greater surface area
How are large fat droplets broken down into smaller ones?
By stomach's mechanical movement
How are small fat droplets prevented from re-aggregating in the GI?
Bile and Phospholipids bind to the surface as emulsifying agents
Why are bile salts and phospholipids good emulsifying agents for fat droplets?
They are amphipathic
Name the bile salt covered in class:
glycocholic acid
What is glycocholic acid?
A bile salt
What limits lipase action on small fat droplets?
Emulsifiers (bile salts and phospholipids)
How does pancreatic lipase gain access to fats covered in emulsifiers?
Secretes amphipathic protein Collipase
Collipase binds to fat droplet and binds lipase
What is collipase?
An amphipathic protein secreted by the pancreas
Binds to fat droplets and Lipase
Facilitates Lipase action on emulsion droplets
What are the two phases for the absorption of fat?
transport into enterocytes
synthesis and transport of cholomicrons out of epithelial cells
What type of Fat digestion products enter the enterocytes?
Fatty acids and Monoglycerides
How do FA and Monoglycerides enter the enterocytes?
passive diffusion down a concentration gradient
What is the difference between Micelles and emulsion droplets?
Micelles are much smaller
They contain digestion products rather than undigested fats
How big are Fat micelles?
4-7 nm
Why is absorption enhanced by fat micelles?
Smaller/greater surface area
Author
kyleannkelsey
ID
217237
Card Set
BIOL 404-Exam 4-GI 6
Description
BIOL 404-Exam 4-GI 6
Updated
5/2/2013, 3:31:05 PM
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