Pharm Final Review

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Author:
LizCintron
ID:
217316
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Pharm Final Review
Updated:
2013-05-02 16:34:21
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pharm
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pharm
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  1. Which antiretroviral class is associated with
    lactic acidosis and hepatic steatosis
    NRTIs
  2. Ganciclovir can be used for the treatment of
    both HSV and CMV infections, however, Acyclovir cannot be used for the
    treatment of HSV infections (T/F)
    false
  3. Red Man's syndrome is a severe allergic reaction that patients may experience during therapy with Vancomycin.  If this
    reaction occurs,  a patient should be treated with an alternative antibiotic and Vancomycin should not be re-challenged in this patient (T/F)
    false
  4. Tetracyclines should be avoided in children under the age of 8 to avoid permanent tooth staining (T/F)
    True
  5. Nephrotoxicity and Ototoxicity are major adverse
    effects of which of the following classes of anti-infectives
    Aminoglycosides
  6. A patient is prescribed Amphotericin B for a
    systemic fungal infection.  Which of the following laboratory tests is the
    most important for the nurse clinician to monitor?
    serum creatinine
  7. What receptor type must the HIV virus have in
    order for the entry inhibitor Marviroc to be effective against the virus
    CCR5
  8. Permethrin is not 100% insecticidal. (T/F)
    True
  9. Malahion is very effective against head lice, but it carries a specifically dangerous potential adverse effect which is:
    flammable
  10. Glucosamine/Chondroitin is primarily used to treat what?
    osteoarthritis
  11. Saw Palmetto has what mechanism of action?
    Inhibits 5-alpha reductase
  12. Silybummarianum is a crazy name to pronounce, but it is Milk Thistle. (T/F)
    true
  13. Which of the following water soluble vitamins are used in energy metabolism, and nerve function.
    B1
  14. This agent should not be used concurrently w
    protease inhibitors due to drug interactions (Cyp450 induction). This agent is
    commonly a part of treatment regimens for TB
    Rifampin
  15. w/ which class of antibiotics that we discussed
    is separation of dose admin w al, mg, containing antacids, iron products, and
    certain vitamins necessary
    tetracyclines fluoroqunolones
  16. major side effecs associated w the use of
    protease inhibitors
    • metabolic disturbances—lipodystrophy fat
    • redistribution hyperlipidemia
  17. zyvox has potential for drug-drug interact w which group or type of drugs
    serotenergic agents—ssr, snri, tca, mao inhibitor
  18. name an AZOLE anti-fungal
    flucanoazole, miconazole
  19. 2 potential adverse effects associated w
    floroquinolone antibiotics—
    QT prolongation and tendinitis
  20. amphotericin class
    polyene (anti fungal)
  21. produce a severe reaction (disulfiram reaction)
    if alcohol consumed
    flagyl
  22. monitor what w daptomycin
    creatine kinase levels
  23. 3rd gen cepholasporin have beter
    activity against which group of organisms compared to 1st gen cepholasporin
    gram neg
  24. pipercillin/tazobactam (zosyn) class
    • peniciliin
    • beta lactamase inhibitor
  25. raltegravir belongs to which drug class
    integrase inhibitor
  26. caspogunfin belongs to which drug class
    echinocandin
  27. major adverse effect of amphotericn
    nephrotoxicity/kidney damage
  28. doxycycline class
    tetracycline
  29. electroylites that need to be
    monitored/supplemented from pts receive amphotericin B
    potassium and magnesium
  30. class of antiretrovirals that’s backbone therapy
    for HIV
    NRTIs
  31. vancomycin antibacterial against which gram +
    organism
    MRSA
  32. side effect of rifamin
    red/orange body fluids
  33. 2 major side effects w aminoglycosides
    nephrotoxicity and ototoxicity
  34. class of antifingual that should be avoided in
    fungal uti due to lack of penetration
    echinocandins
  35. class of antifungal agents the disadvantage of
    inhibit  hepatic cyp450 and increase
    levels of many other drugs
    azoles

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