[TOXICOLOGY] General Toxicology

Poison that causes difficulty in breathing

Poison that causes excessive sneezing

Poison that acts directly on the spinal cord, producing such spasmodic and continuous contraction of muscle

two toxic effect which is considered non threshold effect

Example of Synergism toxicity

It interferes metabolism of ethanol

The effects produced when administration of two substance to an animal lead to toxic response which is entirely different from that of either less than additive

Rate limiting step of isoprenoid synthesis

Antihistamine that can cause cardiac arrhythmias

Active metabolite of terfenadine

Use of (R) enantiomer of thalidomide

Use of (S) enantiomer of thalidomide

Metabolism process that can excrete 95% of acetaminophen

NAPQI stands for

It causes hemolytic anemia by eliciting an autoimmune reaction against Rh factor

Rh factor stands for

Drugs that can cause lupus like syndrome

MOA of sildenafil

MOA of nitroglycerin

Toxicity effect of gingko biloba + NSAIDS

Alkaloid that depletes hepatic glutathione stores thus increase risk of acetaminophen toxicity

long term treatment with dopamine antagonist can result in what side effect

Continued activation of estrogen receptor pathway can lead to what type of cancer

It is characterized by excessive and abnormal collagen disposition in the alveolar intersitium

Drugs that can cause pulmonary fibrosis

Use of tamoxifen

Drug that can cause oligohydramnios, intrauterine growth retardation, renal dysplasia, anuria and renal failure in fetus

Commonly used classes of pesticides

Most common drug that causes red syndrome