BIOL 404-Exam 4-GI 20

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kyleannkelsey
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217338
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BIOL 404-Exam 4-GI 20
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2013-05-02 19:02:54
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BIOL 404 Exam GI 20
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BIOL 404-Exam 4-GI 20
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  1. bile pigments are mostly made up of what?
    Mostly bilirubin
  2. Why is bile yellow?
    Mostly made of billirubin
  3. What is billirubin formed from?
    Heme portion of hemoglobin when damaged RBC’s are digested in spleen and liver
  4. What is formed from the Heme portion of hemoglobin when damaged RBC’s are digested in spleen and liver?
    Bilirubin
  5. What gives feces a brown color?
    Acidified billirubin by bacterial enzymes in the colon
  6. What give urine its yellow color?
    bilirubin
  7. bile salts are synthesized and secreted bywhat?
    hepatocytes
  8. What is the action of bile salts?
    emulsify fats
  9. What are the four main purposes of bile salts?
    • Neutralizes HCl
    • Emulsify fats
    • Cholesterol excretion
    • Aids excretion of metabolic end products
  10. What are components of bile?
    • bicarbonate
    • lecithin
    • cholesterol
    • Metabolic waste
  11. What role does Bile play in Cholesterol secretion?
    Cholesterol is extracted from the blood and excreted in the bile
  12. Approximately what percent of bile salts that enter the small intestine are returned to the liver?
    95%
  13. How are bile salts returned to the liver?
    • Sodium-coupled transporters in the ileum
    • Then, returned via the hepatic portal vein
  14. What is enterohepatic circulation?
    the cycling of bile salts
  15. What percent of bile salts are newly synthesized (uncirculated)
    5%
  16. What hormone controls the flow of bile into the small inetstine?
    CCK
  17. Gastric emptying is inhibited by what?
    fat in the small intestine
  18. What is the size of the small intestine?
    • 1.5 inches diameter
    • 9 ft long
  19. What are the parts of the small intestine?
    • Duodenum
    • jejunum
    • ileum
  20. What is the initial short segment of the small intestine called?
    Duodenum
  21. What is the second 40% of the small intestine called?
    Jejunum
  22. What is the last 60% of the small intestine called?
    ileum
  23. What do Small intestine secretions mainly contain?
    Salt, water, and mucus
  24. What is the purpose of salt, water and mucus secretions of the small inetstine?
    • maintain fluidity
    • solubilize materials in chyme
    • lubricate and protect mucosa
  25. What is the purpose of motility in the small intestine?
    • mixes
    • Brings contents into contact with epithelial cell membrane enzymes and transporters
    • moves undigested material to large intestine
  26. What three places does digestion of nutrient occur in the small intestine?
    • Lumen
    • Epithelial membrane
    • inside epithelial cells (peptidases)
  27. What three types of absorption mechanisms exist in the small intestine?
    • Diffusion
    • Receptor mediated active and passive transport
    • Chylomicron formation
  28. How much water is secreted by the small intestine per day?
    1500mL
  29. Where is water and salt secreted from in the small intestine?
    The base of the villi
  30. What stimuli control the secretion of water into the small intestine?
    • Secretion of electrolytes
    • Presence of hypertonic chyme
  31. What are segmentation contractions of the small intestine?
    Contractions that mix chyme moving it both up and down the GI
  32. What is the purpose of segmentation contraction?
    • Mix chyme with digestion juices
    • Bring chyme in contact with intestinal wall
  33. What causes Segmentation contractions?
    • Food intake
    • Presence of chyme
  34. In the absence of segmentation contractions, what does the small intestine look like?
    A tube
  35. In the presence of segmentation contractions, what does the small intestine look like?
    Ovoid segments
  36. Do segmentation contractions travel?
    No they occur at the same locations
  37. What is the frequency of segmentation contractions?
    • 12 per minute in the duodenum
    • decreasing to 9 per minute in the ileum
  38. How are segmentation contractions are initiated?
    • By slow wave electrical activity generated by pacemaker cells in or associated with the circular smooth muscle layer and is conducted via gap junctions
    • Excitatory neurotransmitters and hormones can enhance this

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