PTG 105-Exam 4-Muscles 3

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PTG 105-Exam 4-Muscles 3
2013-05-05 01:41:02
PTG 105 Exam Muscles

PTG 105-Exam 4-Muscles 3
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  1. What type of cells are the anterior horn cells?
    Nerve cells of the CNS
  2. What type of paralysis do Poliomyelitis patients suffer from?
    Flaccid paralysis
  3. Describe the condition of a person with poliomyelitis:
    • Flaccid paralysis of the arms and legs
    • Difficulty breathing
  4. What is ALS?
    Amyotrophic lateral sclerosis
  5. What is Amyotrophic lateral sclerosis?
    Serious neurological disease that limits voluntary movement
  6. How does Amyotrophic lateral sclerosis begin?
    Muscle twitching/weakness in the arm/leg and slurring of speech
  7. Is there a cure for Amyotrophic lateral sclerosis?
  8. How long do people with Amyotrophic lateral sclerosis live usually?
    3-5 years after first symptoms
  9. Describe progressive stages of Amyotrophic lateral sclerosis:
    • Inability to move muscles needed for eating, speaking, moving and breathing
    • Last stages = difficulty breathing
  10. Describe Myasthenia Gravis:
    • Autoimmune
    • AB destroy neuromuscular junctions
  11. What is the presentation of Myasthenia Gravis?
    Muscle weakness that increases during activity and improves during rest
  12. What disease is marked by Muscle weakness that increases during activity and improves during rest?
    Myastheina Gravis
  13. Describe the immune that leads to Myasthenia Gravis:
    • AB bind (and destroy) ACh receptors on skeletal muscle
    • AutoABs seen in 90% of patients
  14. Do all Myasthenia Gravis patients have autoantibodies?
    No, but 90% do
  15. What type of atrophy is seen with Myasthenia Gravis?
    Disuse atrophy
  16. 2/3 of Myasthenia Gravis patients have_______ and 15% have _______.
    Hyperplasia Thymoma
  17. What What specific muscles are characteristically affected in Myasthenia Gravis?
    • Ocular
    • Causes drooping eyelids and double vision
  18. Describe the presentation of Myasthenia Gravis:
    • Drooping eyelids
    • Double vision
    • Slurred speech
    • Diff. chewing, swallowing
    • Some respiratory/general skeletal muscles maybe effected
  19. What are the two types of treatment for Myasthenia Gravis?
    • Increases Ach at neuromuscular junction
    • Suppress production of abnormal Abs
  20. For Myasthenia Gravis, In what ways can the production of abnormal ABs be thwarted?
    • Thyectomy
    • Plasmapheresis
  21. What is Plasmapheresis?
    Removes autoantibodies
  22. What is Thyectomy?
    Removal of the Thymus
  23. What is the prognosis for pateints with Myasthenia Gravis?
  24. Describe Polymyositis and Dermomyositis:
    • Lymphocytic Inflammatory Autoimmune myopathies
    • Cause symmetrical muscle weakness in large trunk, neck and limbs
  25. What disease is a Lymphocytic inflammatory autoimmune myopathy that effects large muscles of the trunk, neck and extremities?
    Dermatomyositis and Polymyositis
  26. What type of inflammation is found in polymyositis and dermatomyositis?
    Lymphocytic inflammation
  27. What symptom does dermatomyositis have that polymyositis does not?
    Rash on the upper eyelid
  28. What inflammatory muscular disease has a rash on the upprer eyelid?
  29. What symptoms of polymyositis and dermatomyositis be seen on a lab report?
    • Lymphocytic inflammation of the muscle
    • Antinuclear antibodies in the serum
    • Elevated creatine kinase due to muscle injury
  30. Are there lesions of the muscle tissue with dermatomyositis or polymyositis?
  31. Inflammatory myopathies can be caused by dermatomyositis, polymyositis and what else?
    • Viruses: HIV, Influenza
    • Parasitic infections: Trichinosis, Cysticercosis, toxoplasmosis
  32. HIV, Toxoplasmosis, Trichinosis, Cysticercosis and Influenza can all cause what disease?
    Inflammatory myopathy
  33. What are the soft tissues?
    • Fat
    • Muscle
    • Fibrous tissue
  34. What percent of soft tissue tomors are benign?
  35. How do soft tissue tumors present?
    As a Mass
  36. At what age to soft tissue tumors present?
    Any age
  37. What is a malignant soft tissue tumor called?
  38. What is a tumor of the adipose tissue called?
    • Lipoma
    • Liposarcoma
  39. What is a tumor of the smooth muscle called?
    • Leiomyoma
    • Leiyomyosarcoma