PTG 105-Exam 4-Soft Tissue 2

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PTG 105-Exam 4-Soft Tissue 2
2013-05-05 01:43:16
PTG 105 Exam Soft Tissue

PTG 105-Exam 4-Soft Tissue 2
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  1. What is a nodular fasciitis composed of?
    Plump immature fibroblasts or Myofibroblasts
  2. Where do Nodular fasciitis tumors usually present?
    • Forearm
    • Chest
    • Back
  3. How can the growth of nodular fasciitis be characterized?
    Fast Growth
  4. Are the masses of nodular fasciitis painful?
  5. Describe Fibromatosis:
    Benign proliferation of fibroblast and myofibroblasts
  6. What types of Fibromatosis are there?
    • Superficial
    • Deep
  7. Where is superficial fibromatosis found?
    On the palms and penis
  8. Where are deep type fibromatoses found?
    • Abdomen
    • Trunk
    • Limb muscles
  9. Describe histology/pathology of a fibromatosis:
    • Infiltrating borders
    • Firm
    • White cut surface
    • Large
  10. What is the treatment of fibromatosis?
    Surgery, often reoccurring
  11. Describe the aggressiveness of fibromatosis:
    Locally aggressive, does not metastasize distantly
  12. What does Fibromatosis resemble?
  13. What is a desmoid tumor?
    A deep type fibromatosis
  14. When does deep type fibromatosis of the abdominal wall often occur?
    During pregnancy
  15. How common is Fibrosarcoma?
  16. What is the reoccurrence rate of Fibrosarcoma?
  17. What percent of Fibrosarcomas metastasize?
  18. Where do Fibrosarcomas often develop?
    • Thigh
    • Knee
    • Retroperitoneum
  19. What does a Fibrosarcoma look like histologically?
    • Herringbone Fibroblast growth
    • Nuclear atypia
    • Cellular Peomorphism
    • Mitotic activity
  20. What type of tumor shows Herringbone fibroblastic growth patterns?
  21. What are the three type of Fibohistiocytytic tumors?
    • Fibrous histiocytoma
    • Dermatofibrosarcoma protuberans (DFSP)
    • Malignant fibrous histiocytoma
  22. Is Fibrous histiocytoma malignant?
  23. Is Dermatofibrosarcoma protuberans malignant (DFSP)?
    Borderline malignant
  24. What type of Fibrohistiocytic tumor is Malignant?
    FMalignancy fibrous histiocytoma
  25. What type of Fibrohistiocytic tumor is benign?
    Fibrous Histiocytoma
  26. What type of Fibrous histiocytic tumor is borderline Malignant?
    Dermatofibrosarcoma protuberans (DFSP)
  27. How do most benign fibrous histiocytomas usually present initially?
    Mobile subcutaneous nodule on the extremities
  28. What does a Benign Fibrous histiocytoma look like histologically?
    • Storiform pattern
    • Foamy macrophages
    • Tuton giant cells
  29. What disease has a histological appearance of foamy macrophages/storiform pattern/Tuton giant cells?
    Benign Fibrous histiocytoma
  30. What does Storiform pattern of cells look like?
    Star like clustering
  31. Can Dermatofibrosarcoma protuberans metastasize?
    Can, but rarely
  32. Where are Dermatofibrosarcoma protuberans usually found?
    Trunk and proximal extremities
  33. What characteristically happens with Dermatofibrosarcoma protuberans after excision?
    They regrown
  34. Describe Dermatofibrosarcoma protuberans histology:
    • Similar to Benign fibrous histiocytoma
    • More cellular
    • More atypia
    • More mitotic activity
    • Infiltrative borders
  35. Usually, how old are patients with malignant fibrous histiocytoma?
    50-60 years
  36. How often do malignant fibrous histiocytomas metastasize?
    50% of cases
  37. Where are malignant fibrous histiocytomas usually located?
    • Soft tissues of the extremities
    • Retroperitoneum
  38. Describe the histology of malignant fibrous histiocytoma:
    Highly pleomorphic and atypical cells
  39. What is aRhabdomyoma?
    Benign tumor of skeletal muscle