PTG 105-Exam 4-Neural 5
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Is dementia a specific disease?
What is dementia?
Any progressive loss of nerves in the CNS affecting memory and cognitive function
Does having memory loss mean you have dementia?
No dementia is in two or more areas of brain function
What is the most common dementia disease in elderly?
How many people in the US have Alzheimer's?
What age does Alzheimer's usually begin?
65 and up
What proportion of people over 85 have Alzheimer's?
What is a risk factor for Alzheimer's disease?
What area of the brain does Alzheimer's start with?
The part that controls thought memory and language
What is the rate of onset of Alzheimer's disease?
What is the cure for Alzheimer's?
No known cure
What is the treatment for Alzheimer's?
Aricept may slow progression of symptoms
What does Alzheimer's brain look like?
- large Suculi
- Small Gyri
- Large ventricle
- Brain shrivels up
- Plaques and neurofibrous tangles
Where is brain shrinking especially severe in AD patients?
What happens to the ventricles in AD?
They grow larger
What are the most indicative signs of AD?
Plaques and Neurofibrous tangles
What are Neurofibrous tangles and plaques?
- Signs of Alzheimer's disease
- Abnormal clumps and tangled bundles of nerves
What is Parkinson's disease?
Progressive loss of nerve cell function in brain that controls muscle movement
What is the cause of Parkinson's disease?
- Neurons that make dopamine die or stop working
- Reduced dopamine
What does dopamine usually do?
Signaler for coordination of body movement
What disease is marked by the death or lack of function of Brain neurons that secrete dopamine?
When does Parkinson's usually begin?
around age 60
What are the signs of Parkinson's disease?
- Trembling hands, arms, legs, jaw and face
- Stiffness of arms, legs and trunk
- Slow movement
- Poor balance
What is a characteristic symptom of Parkinson's disease?
How is Parkinson's disease diagnosed?
By symptoms, no specific test
What is the treatment for Parkinson's disease?
L-dopa for symptom relief
What is the pathology of the brain in a parkinson's patient?
- loss of pigment in substantia nigra
- Intracytoplasmic inclusions called Lewy bodies
If you examined a brain and saw intracytoplasmic inclusions and loss of pigment in the substantia nigra, what would your diagnosis be?
What is vascular dementia?
Multiple cortical infarcts from previous sustained strokes
What is another name for Vascular Dementia?
Mini infarct dementia
What is the second most common form of dementia?
What is the best form of treatment for Vascular dementia?
Prevention and early detection
What are the risk factors for Vascular dementia?
- Diabetes mellitus
- Peripheral arterial disease
What is Huntington's disease?
Autosomal dominant degeneration of basal ganglia causing dementia and involuntary movements
What is an autosomal dominant disease that affects the basal ganglia andleads to dementia and involuntary movements?
What age is Huntington's disease most common?
How is Huntington's disease aquired?
Autosomal dominant inheritance
What type of tretments are there for Huntington's disease?
Only those for signs and symptoms not for prevention of further progression
If one of your parents had huntington's disease, what are your chances of getting it?
What does Chorea mean?
Dance and refers to quick jerky movements
What would you like to do?
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