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What examples of diseases were given for systemic Mycoses?
What classification of Mycotic diseases are Histoplasmosis and Crytpococcosis?
What mycoses causes causes Histoplasmosis?
Does Histoplasma capsulatum have a capsule?
Where are Histoplasmosis cases found?
- Mid-western U.S.
- 80% of people in Ohio and Mississippi River Valley
What areas do 80% of people test positive for Histoplasma capsulatum infection?
Mississippir river valley and ohio
What places would you expect to find Histoplasma capsulatum?
- Bird/bat dung laden soiled
- Chicken coops
- Construction areas
What three groups of people are most likely to get Histoplasma capsulatum?
- Construction workers
What disease are construction workers, spelunkers and farmers more susceptible to?
Does Histoplasma capsulatum makes spores?
How do people acquire Histoplasmosis?
inhalation of fragments or spores
Describe Systemic mycoses morphology when growing at room temperature?
Describe Systemic mycoses morphology at body temperature?
What percent of people recover and become immune to Histoplasmosis?
- When Histoplasma capsulatum is in the body, what is its morphology?
What percent of people develop flu-like symptoms from a Histoplasma capsulatum infection?
Of the 5% of people that develop flu like symptoms from histoplasmosis, what is the outcome?
- Spontaneous resolution
- Disseminated form develops
Describe the symptoms of disseminate Histoplasmosis:
- Night Sweats
- Weight loss
What is the treatment for disseminated histoplasmosis?
- Amphotericin B
- Oral azoles
Does Disseminated Histoplasmosis need to be treated?