MIC 541-Exam 5-Parisitology 7
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What are the characteristics of Apicomplexan protozoa?
- complex life cycle with >1 host
- Sexual Alternation of generations
What important diseases are cause my apicomplexans?
What proportion of the world's population is affected by Malaria or Toxoplasmosis?
How many children are killed or debilitated by Malaria or toxoplasmosis per year?
Toxoplasmosis and Malaria belong to what parasitic grouping?
What causes malaria?
- 4 species of Plasmodium
- P. vivax
- P. ovale
- P. malariae
- P. falciparum
What is the most deadly malaria causing species?
Where is Malaria epidemic?
- Southern hemisphere
- Where Anopheles mosquitoes are found
What is the vector for Malaria?
Describe the lifecycle of Plasmodium:
- Anopheles mosquitoes gather gametophytes from blood
- gametophytes reproduce in mosquito
- Sporozoites are released into the Mosquito's salivary glands
- Sporozoites are transferred to the host by the mosquito
- Enter the liver
- multiply and release merozoites
- enter RBCs as Trophozoite
- Multiply, re-infect and produce gametophytes
Why does Malaria cause cyclical fevers and anemia?
Due to synchronized release from RBCs
What are the outcomes of Malaria infections?
- Cyclical fever and anemia
- Circulatory problems
- Liver damage
How does malaria cause circulatory issues and liver damage?
- Liver damage= due to lifecycle
- Circulatory issues= due to damaged RBCs in lodging organelle capillaries
What ways can malaria be prevented?
- Avoid mosquitoes
- Chloroquine and Mefloquine prophylaxis
- Malarone and doxycycline in falciparum areas
What medications should you take if in a falciparum area?
Doxycycline or Malarone
How often should prophylactic Chloroquine and Mefloquine be taken?
How often should prophylactic doxycycline or Malarone be taken?
What does Toxoplasma gondii cause?
Where is toxoplasma gondii found?
GI tract of cat
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