MIC 541-Exam 5-Virology 2

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MIC 541-Exam 5-Virology 2
2013-05-07 19:05:42
MIC 541 Exam Virology

MIC 541-Exam 5-Virology 2
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  1. What are the factors of susceptibility to viruses?
    • Number of receptors
    • ability of host to support virus
  2. What type of measurement is Susceptibility?
  3. What is the purpose of a capsid?
    To stabilize and protect the genome
  4. What type of environmental variations are capsids meant to protect against?
    • Temp
    • pH
    • Chemical
  5. What viral structure protects against Temperature, pH and chemical composition of the environment?
  6. What is another word for the viral Nucleocapsid?
  7. What forms the substructure of a viral particle?
    The nucleocapsid
  8. Describe an icosahedral viral shape:
    • 520 triangular surfaces
    • 2,3, and 5 fold axes of symmetry
  9. What type of virus has a Helical formation, as described in class?
    Tobacco mosaic viruses
  10. What is an example of an ovoid virus?
  11. Describe a Helical formation of a virus?
  12. What is a variation of the icosahedrical viral shape?
    Fullerene cone
  13. Describe the composition of viral envelope:
    Lipid bilayer with glycoproteins
  14. Where does the viral envelope reside?
    Outermost layer
  15. What are the advantages of a viral envelope?
    Protects against chemicals and enzymes
  16. What are the disadvantages of a viral envelope?
    Less stable in the environment
  17. How do viruses acquire membranes?
    By budding out of host
  18. What host membranes are viral membranes derived from?
    • Plasma membrane
    • ER
    • Golgi
    • Nuclear membrane
  19. Viral envelope proteins are post-translationally targeted to what?
    The appropriate membrane
  20. How (generally) do viruses replicate?
    • Fusion and host cell entry
    • Replication
    • Assembly
    • Release
    • Maturation
  21. What is the first step in Viral replication?
    • Viral binding to host cell
    • What is require for viral host cell binding?
    • Specific host cell receptors-protein
    • Lipids
    • Carbohydrates