MIC 541-Exam 5-Virology 4
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Do DNA viruses need host machinery for replication?
Depends on the virus (Yes and No)
For enveloped viruses, where does assembly take place?
At the site of envelope acquisition (nucleus, golgi, etc.)
where does core assembly occur for DNA viruses?
In the Nucleus
Where does core assembly occur for RNA viruses?
What are the three ways viruses are released from the host cell:
Describe lytic release of viruses:
- Critical mass is achieved by particle accumulation
- Viral signal induce cell death and virion release
Describe exocytosis of virions from the host cell:
Via normal cellular pathways
When does viral maturation occur:
during or after budding /release
What is the signal for matureation of viruses?
Where do most DNA cell bud off?
What level of disease is caused by most viruses?
No disease at all
What are zoonoses?
Viruses that infect many animals
What are the most common manifestations of viruses:
- Muscle aches
- Respiratory symptoms
- Swollen lymph nodes
What type of infections are associated with RNA viruses?
What RNA viruses are not associated with acute infections?
What are the general body defenses to viruses?
- Cytotoxic T cells
What type of immunity is usually acquired after contact with viruses?
What is the most common viral infection course?
Rapid lytic course
How long can some viruses last in the host:
Chronic infections of years to a lifetime
What are the two types of persistent viral infections?
- Chronic infections
- Latent infections
What are chronic viral infections like?
- Virus is detectable in tissue samples
- multiplies at slow rates
- mild or absent symptoms
What type of persistent viral infection is detectable in tissues, multiplies slowly and has mild or absent symptoms?
What would you like to do?
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