MIC 541-Exam 5-Virology 8
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What is the DNA viral group that infects humans?
- Enveloped double stranded
- Non-enveloped -single and double stranded
What are the three main enveloped DNA viruses?
- Pox virus
- Herpes virus
What type of viruses are the Pox virus, Hepadnavirus and Herpes virus?
Enveloped DNA viruses
Describe the symptoms of Poxviruses:
eruptive skin pustules (pox or pucks)
What are the largest and most complex animal viruses?
What type of human virus has the largest genome?
How do Poxviruses multiply?
in the cytoplasm (factory areas)
What cells do poxviruses have specificity for?
cytoplasm of epidermal cells and subcutaneous tissue
What type of virus has specificity for subcutaneous and epidermal tissues?
What are the human poxvviruses?
What does Orthopoxvirus cause?
Smallpox (Variola virus)
What type of Poxvirus causes smallpox or Variola virus?
What type of Pox virus is Molluscum contagiosum virus?
Describe the structure of the pox virus from outer to inner:
- Surface tubules
- Outer membrane
- Lateral bodies
- Core membrane
Where does maturation of the Poxvirus occur?
In the cytoplasm
Before uncoating, what molecules does the Poxvirus emit?
Why does the Poxvirus emit early mRNA molecules (prior to uncoating)?
- They code for polymerases, transcription factors
- Growth factors and immune response defense molecules
What are the last three steps of Pox virus replication, prior to exiting the cell?
- Golgi Wrapping
- Actin tail addition
Where does Pox viral replication occur in the cell?
In the cytoplasm
What does small pox look like?
Pustules all over the body
What was the first disease to be eradicated by Vaccine?
How are people exposed to smallpox?
inhalation or skin contact
What would you like to do?
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