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What area does HSV-2 lay dormant in?
What HSV strain lays dormant in the sacral ganglia?
What HSV strain lays dormant in the trigeminal ganglia?
What is HSV-1 an etiological agent for?
- Herpes labialis
- Ocular herpes
What is HSV-2 and etiological agent for?
What is the most significant transmission route for Herpes viruses?
Direct contact with active lesions
Where does HSV multiply at?
After HSV multiplies in sensory neurons what happens?
moves to appropriate ganglia
How does HSV-1 enter the Ganglia?
Through the 5th cranial nerve
How does HSV-2 enter the ganglia?
Lumbosacral spinal nerve trunk ganglia
What are triggers for recurrent HSV infection?
- UV radiation
- Mechanical injury
How does recurrent viral infection occur?
Newly formed viruses migrate to the body surface producing local effects
The trigeminal nerve has three branches as it nears the face, what are they?
- Maxillary branch
- Mandibular branch
- Ophthalmic branch
The Maxillary, Mandibular and Ophthalmic nerves converge on a single ganglia called what?
The Trigeminal ganglia
What is the most common recurrent HSV infection?
What are the lesions of Herpes labialis?
How long does it take for Herpes labialis infections to resolve?
- 2-3 days they crust over
- 14 days they are healed
Where do herpes labialis lesions occur?
At the mucocutaneous junction of the lips or adjacent skin
What HSV causes infection of the oropharynx in young children?
What does Herpes gingivostomatitis cause?
Infection of the oropharynx in young children
What are symptoms of Herpes gingivostomatitis?
- Sore throat
- Swollen lymph nodes
What is Herpetic keratitis?
What causes ocular herpes?
What are the symptoms of herpetic keratitis?
- Gritty feeling in the eye
- inflammation of the eye
- sharp eye pain
- Light sensitivity