MIC 541-Exam 5-Virology 13

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kyleannkelsey
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218471
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MIC 541-Exam 5-Virology 13
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2013-05-08 00:36:16
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MIC 541 Exam Virology 13
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MIC 541-Exam 5-Virology 13
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  1. What general type of drug is Acyclovir?
    Nucleoside analog
  2. What is the most potent anti-herpetic medication?
    Acyclovir
  3. What is Famciclovir and Penciclovir?
    Acyclic nucleoside analogs of guanosine
  4. How do Famciclovir and Penciclovir compare to Acyclovir?
    • Fam and Pen are less potent that Acyclovir
    • Fam and Pen have better uptake and half-life
  5. What drugs is an L-valyl ester of acyclovir?
    Valacyclovir
  6. What virus causes Chicken pox and shingles?
    Varicella-Zoster virus
  7. What type of virus is VZV?
    Herpes virus
  8. What hosts can VZV infect?
    Humans only
  9. How is VZV acquired?
    • Respiratory/Airborne
    • Aerosol/droplets
  10. How long after VZV inoculation do lesions appear?
    1-2 days
  11. What is a characteristic lesion of Varicella virus?
    Vesicles (chicken pox)
  12. What are the treatments for VZV?
    • Acyclovir
    • Famciclovir
    • interferon for systemic disease
  13. What would you use to treat systemic VZV?
    Interferon
  14. What type of vaccine is available for VZV?
    Live attenuated
  15. What is disease is caused by zoster?
    Shingles
  16. What disease is caused by Varicella?
    Chicken pox
  17. What activate the zoster virus?
    Stress
  18. What cells are characteristic of Cytomegalovirus?
    Giant cells with nuclear and cytoplasmic inclusions
  19. How are Cytomegaloviruses transmitted?
    • Saliva
    • Breast milk
    • Urine
    • Semen
    • Cervical secretions
  20. Where doe Cytomegalovirus lay dormant?
    Many tissues
  21. What percent of adults are infected with Cytomegalovirus?
    70-90%

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