MIC 541-Exam 5-Virology 14

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kyleannkelsey
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MIC 541-Exam 5-Virology 14
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2013-05-08 00:36:59
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MIC 541 Exam Virology 14
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MIC 541-Exam 5-Virology 14
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  1. What virus causes Giant cells with nuclear and cytoplasmic inclusions?
    Cytomegalovirus
  2. What are the common symptoms for Cytomegalovirus?
    Usually asymptomatic
  3. What symptoms of Cytomegalovirus are seen in newborns?
    • Enlarged liver and spleen
    • Jaundice
    • Capillary bleeding
    • Microcephaly
    • ocular inflammation
    • Fatality
  4. babies that survive Cytomegaloviral infections have what prolonged symptoms?
    • Neurological sequelae
    • Hearing and visual disturbances
    • Mental retardation
  5. Perinatal CMV infections have what symptoms?
    • Asymptomatic
    • pneumonitis
    • mononeucleosis like syndrome
  6. What does CMV cause in AIDS patients?
    • CMV mononucleosis
    • Disseminated CMV
    • retinitis
  7. What can CMV cause in transplant patients?
    • Pneumonitis
    • hepatitis
    • myocarditis
    • meningoencephalitis
  8. What treatment for CMV is given to the immunocomprimised?
    • Ganciclovir (Acyclovir analog)
    • Foscarnet
  9. What is Ganciclovir?
    Acyclovir analog that is more effective against CMV
  10. What is Foscarnet?
    • non-nucleoside inhibitor of viral DNA polymerase
    • Used to treat CMV
  11. What part of the body does EBV infect?
    Lymphoid tissue and Salivary glands
  12. Where is EBV found in the environment?
    Ubiquitous
  13. What is the route of transmission for EBV?
    • Direct oral contact
    • Contamination with saliva
  14. What does EBV cause?
    infectious mononucleosis
  15. What group is susceptible to EBV in industrialized countries?
    College aged population
  16. By mid-life, what percent of people have gotten EBV?
    90-95%
  17. What are the symptoms of infectious mononucleosis?
    • Sore throat
    • High fever
    • Cervical Lymphadenopathy
  18. What is the incubation period for infectious mononucleosis?
    30-50 days
  19. Can EBV be reactivated?
    Yes, usually less severe
  20. Where does EBV lay dormant?
    B cells
  21. What virus lays dormant in the B cells?
    EBV
  22. What are the complications of EBV?
    • Burkitt lymphoma
    • Nasopharyngeal carcinoma

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