MIC 541-Exam 5-Mycology 12
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What is another name for miconazole?
What is another name for monistat?
What antifungal is used as a replacement for Nystatin?
Myconazole and Clotrimazole
Whatare the side effects of Imidazoles?
- Host steroid metabolism problems (menstruation and male breast enlargement)
- Liver toxicity
What is the more common imidazole side effect?
What drug causes male breast enlargement and menstruation irregularities?
What are Triazoles
Imidazoles with an extra N in the azole ring
What are the side effects of Triazoles?
Same as imidazoles (host steroid metabolism and liver toxicity issues)
Give four examples of triazoles
How many triazole rings are found in fluconazole?
What is fluconazole used for?
Meningitis, good CNS levels
Describe an Echinocandin:
Large cyclic compounds that inhibit B-(1,3)-D-glucan synthesis
What is the action of Echinocandins?
Inhibits cross wall formation in fungal call walls
What anti-fungal inhibits cross-wall formation in fungal cell walls?
What is an example of an Echinocandin?
What type of Antifungal is Caspofungin?
What are Echinocandins used to treat?
- Candida infection
What type of side effects do Echinocandins have?
What drugs are Echinocandins synergistic with?
Amphoteracin B and azoles
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