MIC 541-Exam 5-Mycology 12

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kyleannkelsey
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218550
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MIC 541-Exam 5-Mycology 12
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2013-05-08 10:55:28
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MIC 541 Exam Mycology 12
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MIC 541-Exam 5-Mycology 12
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  1. What is another name for miconazole?
    Monistat
  2. What is another name for monistat?
    Miconizole
  3. What antifungal is used as a replacement for Nystatin?
    Myconazole and Clotrimazole
  4. Whatare the side effects of Imidazoles?
    • Host steroid metabolism problems (menstruation and male breast enlargement)
    • Liver toxicity
  5. What is the more common imidazole side effect?
    Liver toxicity
  6. What drug causes male breast enlargement and menstruation irregularities?
    Imidazoles
  7. What are Triazoles
    Imidazoles with an extra N in the azole ring
  8. What are the side effects of Triazoles?
    Same as imidazoles (host steroid metabolism and liver toxicity issues)
  9. Give four examples of triazoles
    • Flucanazole
    • Itraconazole
    • Voriconazole
    • Posaconizole
  10. How many triazole rings are found in fluconazole?
    2
  11. What is fluconazole used for?
    Meningitis, good CNS levels
  12. Describe an Echinocandin:
    Large cyclic compounds that inhibit B-(1,3)-D-glucan synthesis
  13. What is the action of Echinocandins?
    Inhibits cross wall formation in fungal call walls
  14. What anti-fungal inhibits cross-wall formation in fungal cell walls?
    Echinocandins
  15. What is an example of an Echinocandin?
    • Caspofungin
    • Micafungin
    • Anidulafungin
  16. What type of Antifungal is Caspofungin?
    Echinocandin
  17. What are Echinocandins used to treat?
    • Candida infection
    • Aspergillus
  18. What type of side effects do Echinocandins have?
    Remarkably non-toxic
  19. What drugs are Echinocandins synergistic with?
    Amphoteracin B and azoles

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