ASD and FXS

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Author:
thayman1
ID:
221287
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ASD and FXS
Updated:
2013-05-27 04:56:27
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  1. What is Fragile X
    Hagerman and Hagerman 2002: genetic cause of intellectual disability
  2. Genetics of Fragile X
    on x chromosome-> CGG repeats in FMR1-> shuts down production of FMRP (important for brain development)
  3. Hagerman and Hagerman 2002
    autistic characteristics: repetitive behaviours, poor eye contact, social avoidance
  4. Rodgers et al 2001
    50% of males may also have autism
  5. Roberts et al 2001
    • language is more impaired than expected for cognitive ability
    • worse in production
  6. Lewis et al 2006
    fxs with asd worse on receptive language
  7. Garner et al 1999
    fxs group performed worse on tom than id matched group (like grant et al 2007)

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