Dopamine hypothesis:Dysfunction in neurotransmission > dopamine activation involving the midbrain, cortex and limbic system.
Altered brain structure hypothesis:Volume reduction affecting the amygdala, frontal, and temporal lobes, hippocampus, thalamu relays have been noted. Ventricular enlargement is common. Reduced lateralization and altered lateralization.
What are the positive symptoms of schizophrenia?
Hallucinations; visual, auditory, olfactory
Bizarre and unpredictable behaviour
What are the negative symptoms?
Normal thoughts and behaviours are absent or diminished.
What are the cognitive symptoms?
Poor executive functioning - unable to understand info and use this to make a decision.
Trouble focussing or paying attention
Unable to utilise new information.
Are things a person can experience that no one else is experiencing. Can affect any of the senses.
Fixed false beliefs. No amount of evidence can change them to make patients believe they are false. Not logically - frequently bizarre.
Define thoughts disorder?
Disorganised thinking. Unusual/dysfunctional thought processes/way of thinking. Trouble linking thoughts in a logical way or organising thoughts-fast disorganised speech-jumping rapidly from topic to topic.
Define movement disorders?
Agitated body movements-pacing, repetitive movements/actions
What is the medication for schizophrenia?
What is the mode of action?
Blocks dopamine receptors in the brain and controls psychotic symptoms.