Potassium wasting diuretic. Edema due to heart failure, hepatic impairment or renal disease. Therapeutic Effects: Diuresis and subsequent mobilization of excess fluid (edema, pleural effusions). Decreased blood pressure. Assess fluid status. Monitor daily weight, intake and output ratios, amount and location of edema, lung sounds, skin turgor, and mucous membranes. Notify physician or other health care professional if thirst, dry mouth, lethargy, weakness, hypotension, or oliguria occurs. Potassium supplements or potassium-sparing diuretics may be used concurrently to prevent hypokalemia.