ANS Pharm

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Author:
nedi
ID:
223422
Filename:
ANS Pharm
Updated:
2013-06-11 14:40:21
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ans
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  1. Bethanechol CLINICAL APPLICATIONS?
    • Direct Cholinomimetic Agonist
    • Postoperative ileus, neurogenic ileus, and
    • urinary retention
  2. Carbachol CLINICAL APPLICATIONS?
    • Direct Cholinomimetic Agonist
    • Glaucoma, pupillary contraction, and relief of
    • intraocular pressure
  3. Pilocarpine CLINICAL APPLICATIONS?
    • Direct Cholinomimetic Agonist
    • Potent stimulator of sweat, tears, and saliva
    • Open-angle and closed-angle glaucoma
  4. Methacholine CLINICAL APPLICATIONS?
    • Direct Cholinomimetic Agonist
    • Challenge test for diagnosis of asthma
  5. Bethanechol ACTION?
    • Direct Cholinomimetic Agonist
    • Activates bowel and bladder smooth
    • muscle; resistant to AChE. "Bethany, call
    • (bethanechol) me, maybe, if you want to
    • activate your bowels and bladder."
  6. Carbachol ACTION?
    • Direct Cholinomimetic Agonist
    • Carbon copy of acetylcholine.
  7. Pilocarpine ACTION?
    • Direct Cholinomimetic Agonist
    • Contracts ciliary muscle of eye (open-angle
    • glaucoma), pupillary sphincter (closed-angle
    • glaucoma); resistant to AChE. "You cry, drool,
    • and sweat on your 'pilow.' "
  8. Methacholine ACTION?
    • Direct Cholinomimetic Agonist
    • Stimulates muscarinic receptors in airway when
    • inhaled.
  9. Neostigmine CLINICAL APPLICATIONS?
    • anticholinesterase
    • Postoperative and neurogenic ileus and
    • urinary retention, myasthenia gravis,
    • reversal of neuromuscular junction blockade
    • (postoperative)
  10. Pyridostigmine CLINICAL APPLICATIONS?
    • anticholinesterase
    • Myasthenia gravis (long acting); does not
    • penetrate CNS
  11. Edrophonium CLINICAL APPLICATIONS?
    • anticholinesterase
    • Diagnosis of myasthenia gravis (extremely short
    • acting)
  12. Physostigmine CLINICAL APPLICATIONS?
    • anticholinesterase
    • Anticholinergic toxicity (crosses blood-brain
    • barrier - CNS)
  13. Donepezil CLINICAL APPLICATIONS?
    • anticholinesterase
    • Alzheimer's disease
  14. Neostigmine ACTION?
    • anticholinesterase
    • (+) endogenous ACh.
    • Neo CNS =No CNS penetration.
  15. Pyridostigmine ACTION?
    • anticholinesterase
    • (+) endogenous ACh; (+) strength. Pyridostigmine
    • gets rid of myasthenia gravis
  16. Edrophonium ACTION?
    • anticholinesterase
    • (+) endogenous ACh.
  17. Physostigmine ACTION?
    • anticholinesterase
    • ^ endogenous ACh. Physostigmine "phyxes"
    • atropine overdose.
  18. Donepezil ACTION?
    • anticholinesterase
    • ^ endogenous ACh.
  19. Atropine, homatropine, tropicamide ORGAN SYSTEMS?
    • Muscarinic antagonists
    • Eye
  20. Benztropine ORGAN SYSTEMS?
    Muscarinic antagonist CNS
  21. Scopolamine ORGAN SYSTEMS?
    • Muscarinic antagonist
    • CNS
  22. lpratropium, tiotropium ORGAN SYSTEMS?
    • Muscarinic antagonist
    • Respiratory
  23. Oxybutynin ORGAN SYSTEMS?
    • Muscarinic antagonist
    • Genitourinary
  24. Glycopyrrolate ORGAN SYSTEMS?
    • Muscarinic antagonist
    • Gastrointestinal, respiratory
  25. Atropine, homatropine, tropicamide APPLICATIONS?
    • Muscarinic antagonist
    • Produce mydriasis and cycloplegia
  26. Benztropine APPLICATIONS?
    • Muscarinic antagonist
    • Parkinson's disease- "Park my Benz"
  27. Scopolamine APPLICATIONS?
    • Muscarinic antagonist
    • Motion sickness
  28. lpratropium, tiotropium APPLICATIONS?
    • Muscarinic antagonist
    • COPD, asthma ("' pray I can breathe soon!")
  29. Oxybutynin APPLICATIONS?
    • Muscarinic antagonist
    • Reduce urgency in mild cystitis and reduce
    • bladder spasms
  30. Glycopyrrolate APPLICATIONS?
    • Muscarinic antagonist
    • Parenteral: preoperative use to reduce airway
    • secretions
    • Oral: drooling, peptic ulcer
  31. Atropine Action?
    • pupil dilation
    • decreased airway secretions
    • reduced stomach acid
    • decrease gut motility
    • decrease bladder urgency in cystitis
    • Tx for OP poisoning
  32. Atropine Toxicity?
    • Hot as a hare
    • Dry as a bone
    • Red as a beet
    • Blind as a bat
    • Mad as a hatter
    • Jimson weed (Datura)
  33. Epinephrine?
    • Direct sympathomimetics
    • A12, b12
    • Anaphylaxis, glaucoma (open angle), asthma,
    • hypotension
  34. Norepinephrine?
    • Direct sympathomimetics
    • A12, b1
    • Hypotension (but decres. renal perfusion)
  35. Isoproterenol?
    • Direct sympathomimetics-b12
    • Torsacle de pointes (tachycardia decreases dec. QT
    • interval), braclyarrhythmias (but can worsen
    • ischemia)
  36. Dopamine?
    • Direct sympathomimetics-A12B12D1
    • Shock (renal perfusion), heart failure; inotropic and chronotropic
    • (high (high (medium (medium (low
  37. Dobutamine?
    • Direct sympathomimetics-B1
    • Heart failure, cardiac stress testing; inotropic
    • and chronotropic
  38. Phenylephrine?
    • Direct sympathomimetics-A12
    • Hypotension (vasoconstrictor), ocular
    • procedures (mydriatic), rhinitis (decongestant)
  39. Albuterol, salmeterol, terbutaline?
    • Direct sympathomimetic-B2
    • Metaproterenol and albuterol for acute asthma; salmeterol for long-term asthma or COPD
    • control; terbutaline to reduce premature
    • uterine contractions
  40. Phenoxybenzamine Use?
    • Nonselective a-blocker
    • Pheochromocytoma
  41. Prazosin, terazosin, doxazosin, tamsulosin Use?
    • a1 selective blocker (-osin ending)
    • Hypertension, urinary retention in BPH
  42. Mirtazapine Use?
    • a2 selective blocker
    • Depression

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