Combination of clarithromycin/azithromycin and ethambutol with or without rifabutin
Pulmonary MAC: 6 months/~90% chance of recovery
Disseminated disease: Maintenance therapy for life
Patients with low CD4+ counts get prophylactic TX w/HAART
Lymphadenitis in kids: no treatment necessary/benign course
Which mycobacteria Requires hemin for growth; (chocolate plate or Middlebrook agar with “X” factor strip); Prefers 30°C and primarily causes skin and joint disease in AIDS patients
Which mycobacteria is most often seen in immunocompromised patients and the disease progression resembles TB-chronic pulmonary disease?
What are the key biochemicals in identifying M. kansasii?
Photo Positive, Nitrate Positive, Accuprobe available
This organism is found in Fresh and Salt water and primarily causes cutaneous infections due to water-related trauma (fish tank, swimming pool, or natural water sources), prefers 30°C.
What organisms are considered schrotochromogens?
M. scrofulaceum and M. gordonae
What important pathogen is a cause of cervical lymphadenitis in children <5 years old and has been surpassed by M. avium complex as most common cause of lymphadenitis in developed countries?
This organism is very commonly found in water; Non-pathogenic
Most commonly encountered “contaminant” in AFB Lab; Used as QA monitor to evaluate decontamination procedure; ~5% of total isolates should be M. gordonae:
What mycobacteria are considered rapid growers?
M. fortuitum complex, M. leprae,
Why is it important to differentiate M. fortuitum from M. chelonae? How are they differentiated?
M. chelonae is much more resistant
M.fortuitum species group:Salt tolerance, Iron uptake, and Nitrate POS
M. chelonae: Salt Tolerance, Iron Uptake, and Nitrate NEG
What mycobacteria causes Hansen's disease?
Which mycobacterium does not grow on routine Media; Requires Cell Culture because it is characteristic of an Intracellular “parasite”?