If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is demonstrating:
B. Linkage disequilibrium
Dosage is defined as an antibody reacting stronger with homozygous cells (such as KK) than with heterozygous cells (such as Kk). In addition to Kell, dosage effect is seen commonly with antigens M, N, S, s, Fya, Fyb, Jka, Jkb, and the antigens of the Rh system.
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