Blood Banking: Genetics and Immunology of Blood Groups

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mbailey585
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224813
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Blood Banking: Genetics and Immunology of Blood Groups
Updated:
2013-06-23 22:33:45
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Genetics Immunology Blood Groups
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Genetics and Immunology of Blood Groups
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  1. What type of serological testing does the blood bank technologist perform when determining the blood group of a patient?

    A. Genotyping
    B. Both genotyping and phenotyping
    C. Polymerase chain reaction
    D. Phenotyping
    D. Phenotyping

    the physical expression of a genotype, is the type of testing routinely performed in the blood bank. An individual, for example, may have the AO genotype but phenotypes as group A.
    (this multiple choice question has been scrambled)
  2. If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is demonstrating:

    A. Dosage
    B. Linkage disequilibrium
    C. Homozygosity
    D. Heterozygosity
    A. Heterozygosity

    Dosage is defined as an antibody reacting stronger with homozygous cells (such as KK) than with heterozygous cells (such as Kk). In addition to Kell, dosage effect is seen commonly with antigens M, N, S, s, Fya, Fyb, Jka, Jkb, and the antigens of the Rh system.
    (this multiple choice question has been scrambled)
  3. Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expression of none of these antigens. What factor(s) may account for the absence of these antigens in James?

    A. Medication
    B. Gender and race
    C. Gender
    D. Race
    B. Gender and race

    The frequency of Duffy antigens Fya and Fyb varies with race. The Fy(a-b-) phenotype occurs in almost 70% of African Americans and is very rare in whites. The Xga antigen is X-linked and, therefore, expressed more frequently in women (who may inherit the antigen from either parent) than in men.
    (this multiple choice question has been scrambled)

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