-
acute?
- sudden onset
- limited duration
-
recurrent
- repeated episodes
- separated by periods of inactivity wo tx
-
chronic
persistent with relapse after discontinuing tx
-
AAU?
- sx: sudden, uni pain, RE, photo/tear
- signs: ciliary inj, pink epis vessels, constricted sluggish pupil, endo cell dusting, flare, synechiae, hypopyon
-
ant chamber in AAU?
- cells in aqueous: leukocytes, RBC, pigment cells moving upwards
- flare: protein leaking from inflamed iris/ciliary body-> breakdown of BAB
-
CAU?
- granulomatous- large deposits of macrophages, plasma/giant cells
- nongran- small precipitates and lymphocytes
- bilateral
-
CAU sx?
- asymptomatic
- aqueous cells- variable
- flare
- iris nodules- koeppe and busacca
- KP- lympho, neutro, epitheloid
- Large KP (granulomatous)- greasy, muttonfat KP glassy appearance
-
2ndy complications of CAU?
cataract and glaucoma
-
TX of AAU and CAU?
- cyclopegic- break synechiae, relieve ciliary muscle spasm and pupillary sphincter
- steroids- AAU- taper frmo intensive, CAU- long term weak dose
-
HLA-B27+ uveitis?
- uni, KP nongran
- M>F
- assoc disease
- severe, acute, reccurent
-
HLA B27- uveitis?
- M=F
- non assoc disease
- chronic
- loss of vis
-
HLA B27 spondylarthropathies?
- ankylosing sponylitis
- reiter- reactive arthiritis, mild, bi, muco
- psoriatic arthritis- NSAIDS, psoriasis
- juvenile idiopathic arthritis- CAU, nongran, bi, asymptomatic, small KP NO HYPOPYON, post synechiae, dusting of corn end
-
Sarcoidosis?
- gran, inflammatory disorder
- sx: mutton fat KP, iris nodules, trab nodules, snowball vitreous opacities, AAU and CAU, DE
- tx: steroids
-
Behcet?
- HLA B51
- east med and japan
- bil, 30 yo M
-
sx behcet?
- blurr, photo, pain, floaters
- AAU: recurrent, flare, inflam cells in AC, KPs, hypopyon
- tx: steroids
-
VKH?
- idio, inflam, auto-> melanocytes
- alopecia, vitiligo, poliosis
- F, 20-50
- sx: bi, chronic, diffuse gran, ant and post
-
Viral?
- simplex- gran, chronic, atrophy, steroids
- zoster: atrophy, steroids, asymp/mild
- congenital rubella: AU-> atrophy
-
Bacterial uveitis?
- TB-> chronic granulomatous ant uve
- syphilis- chronic gran
- lyme
- cat scratch- toxoplasmosis
-
Fuch's heterocrhomic cyclitis?
- CAU non granulomatous
- uni F>M, young
- present: floaters, blurring, PSC, heterochromia
-
SX of fuch's?
- no synechiae
- KP small, stellate, grey white, scattered
- transparent nodules at pupillary border
- low flare and cells
- diffuse iris atrophy-> heterochromia
- complications: cataract and glaucoma
-
lens induced uveitis?
- immune response to lens proteins
- phacoanaphylactic endophthalmitis: gran AU, Inc IOP
- non gran phacoanaphylactic uveitis- less sever than other
- tx: steroids
-
sympathetic ophthalmia
- RF: trauma and intraocular surgery
- bi, granulomatous panuveitis
- sx: blurry, pain, photophobia
- ddx: VKH- no trauma, sarcoidosis,
- tx: EMERGENCY
-
intermediate uveitis
- idio
- sx: plars planitis (snowball formation), AU, vascular changes in retina, vitreous condensation, blur, floaters
- tx: benign, may not require treatment
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