Endocrine

  1. cAMP
    • FSH, LH
    • CRH, ACTH, MSH
    • TSH, PTH, calcitonin
    • ADH (V2 receptor)
    • hCG
    • GHRH
    • glucagon

    FLAT CHAMP
  2. cGMP
    ANP, NO (a type of "edothelium-derived relaxing factor" (EDRF))

    - ANP released in response to high blood pressure. Exact opposite effect of aldosterone

    Think vasodilators
  3. IP3
    • GnRH, Oxytocin
    • TRH
    • angiotensin II, ADH (V1 receptor)
    • histamine (H1), gastrin
    • GHRH (minor role)
  4. Steroid receptor
    Cytosolic:

    • Vitamin D
    • Estrogen, Progesterone, Testosterone
    • Cortisol
    • Aldosterone

    Nuclear:

    T3/T4
  5. Intrinsic tyrosine kinase
    (MAP kinase pathway)
    • Insulin
    • IGF-1, FGF, PDGF, EGF

    • Think growth factors
    • "MAP out the growth"
  6. Receptor-associated tyrosine kinase
    (JAK/STAT pathway)
    • GH, prolactin (acidophiles)
    • Immunomodulators (e.g. cytokines IL-2, IL-6, IL-8, IFN)
  7. Somatotrope

    anterior pituitary cell that releases...
    GH
  8. Thyrotrope

    anterior pituitary cell that releases...
    TSH
  9. Lactotrope

    anterior pituitary cell that releases...
    PRL
  10. Gonadotropes

    anterior pituitary cell that releases...
    FSH, LH
  11. Corticotropes

    anterior pituitary cell that releases...
    ACTH
  12. Acidophile hormones
    • Somatotropes - GH
    • Lactotropes - PRL
  13. Basophile hormones
    • Thyrotropes - TSH
    • Gonadotropes - FSH, LH
    • Corticotropes - ACTH, MSH
Author
certainlygirl
ID
225300
Card Set
Endocrine
Description
Signaling pathways of endocrine hormone
Updated