A Pharm - Diuretics

Card Set Information

Author:
bgroll
ID:
226321
Filename:
A Pharm - Diuretics
Updated:
2013-07-08 13:16:06
Tags:
aa emory
Folders:

Description:
exam 3
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user bgroll on FreezingBlue Flashcards. What would you like to do?


  1. What is the mechanism of action of Thiazides?
    Where is the site of action?
    Thiazides are ___ _______.
    • inhibit Na and Cl reabsorbtion
    • ascending loop of henle
    • K wasting
  2. Name 4 thiazides:
    • Chlorothiazide
    • hydrochlorothiazide
    • benzthiazide
    • cyclothiazide
  3. Clinical uses of Thiazides:
    • essential HTN
    • Edema
    • Diabetes insipidus
    • hypercalcemia
  4. What are the short and long term affects of Thiazides?
    • short term:  decrease extracellular volume and CO
    • long term:  peripheral vasodilation.
  5. What is the major side effect of Thiazides?
    • HypoK HypoCl metabolic acidosis
    • dysrhthmias
    • HYPERURICEMIA (gout aggravation)
    • renal and hepatic failure?
  6. Name two LOOP Diuretics:
    • Ethacrynic Acid
    • Furosemide
  7. Loop diuretics _______ ___ reabsorption in the medullary portion of ascending ____ __ _____.
    • inhibit ion
    • loop of henle
  8. Loop diuretics are NOT USED to treat _________ ___.
    Essential HTN
  9. What are 3 clinical uses for Loop diuretics?
    • Edema mobilization
    • ICP tx (but mannitol preferred)
    • Diff dx of oliguria
  10. What are side fx of LOOP Diuretics?
    • fluid/ ion imbalance
    • hypokalemia
    • increase digitalis tox
    • potentiate NMB's
    • Hyperuricemia
    • Aminoglycoside tox (by inc plasma conc)
    • sulfonamide allergy (sulfur in molecule!)
  11. Pt's with a sulfonamide allergy may be allergic to what diuretic?
    Loop
  12. Name 2 Osmotic Diuretics:
    • Mannitol
    • Urea
  13. Osmotic Diuretics are freely filterable at the __________, undergo _______ reabsorption, ______ __________, and are pharmacology _____.
    • glomerulus
    • limited
    • resist metabolism
    • inert
  14. What is the mechanism of action of Osmotic Diuretics?
    • increases osmolarity of renal tubular fluid, prevents reabsoption of water.
    • increase plasma osmolarity
  15. Name clinical uses for Osmotic Diuretics include prophylaxis against _____ _______, diff dx of ________, tx of increased ___, and reduction of _____________ pressure.
    • renal failure
    • oliguria
    • ICP
    • intraocular
  16. Two K+ sparing diuretics include, T__________, and A________.
    • Triamterene
    • Amiloride
  17. What area of the kidneys do K+ sparing diuretics affect? Why are the used? What is a side effect?
    • convoluted tubules
    • used with other diuretics or in place of a diuretic if low K+ is a concern
    • HYPERKALEMIA
  18. What are the side effects of Osmotic Diuretics?
    • Pulmonary Edema
    • Hypovolemia
    • Electrolyte imbalance
    • plasma hyperosmolarity
  19. Name one Aldosterone Antagonist:  What is a clinical use?
    • Spirinolactone
    • tx of ascites
  20. Carbonic anhydrase inhibitors include the drug A____________, which fx the __________ ducts and inhibit ______ reabsoption.  They are used clinically for ___ surgery.
    • Acetazolamide
    • collecting
    • NaHCO3
    • EYE

What would you like to do?

Home > Flashcards > Print Preview