Toxins and antidotes

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Author:
Anonymous
ID:
226475
Filename:
Toxins and antidotes
Updated:
2013-07-09 16:12:37
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toxins
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toxins
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  1. Acetaminophen
    • N acetyl cysteine
    • If recent ingestion, n acetyl
    • If > 24 hrs ago, no rx
    • If unclear amount- drug level
    • Remember charcoal is not c/i in acetominophen tox
  2. Acid/alkali
    upper endoscopy to eval for stricture
  3. organophosphates
    atropine, pralidoxime
  4. anticholinergics
    physostigmine
  5. arsenic, mercury, gold
    succimer, dimercaprol
  6. b-blocker
    glucagon
  7. barbiturates
    urine alk, dialysis, act charcoal
  8. benzo
    flumazenil, can cause w/d seizure
  9. black widow bite
    calcium gluconate
  10. C0
    100% o2 and hyperbaric oxy
  11. copper, arsenic, lead, gold
    penicillamine
  12. cyanide
    hydroxycobalamin, amyl nitrate, sodium nitrate, sodium thiosulfate
  13. digitalis and what increases toxicity?
    • Remember: quinidine, cimetidine, amiodarone and CCBs all inc risk of dig toxicity
    • Rx: normalize K, anti dig Fab
  14. Heparin
    protamine sulfate
  15. INH
    pyridoxine
  16. Iron
    defexeroxime
  17. Lead
    succimer, CaEDTA, dimercaprol
  18. Methanol/ethylene glycol
    ETOH, fomepizole, dialysis, calcium gluconate if ethylene glycol
  19. methemoglobin
    methylene blue
  20. opiod
    naloxone
  21. salicylate
    • Sx: tinnitis, renal tox
    • URine alkalinization, dialysis, activated charcoal
  22. TCA
    sodium bicarb, diazepam for seizure
  23. tpa, streptokinase
    aminocaproic acid
  24. Warfarin
    FFP and Vit K

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