Flumazenil

Card Set Information

Author:
Ritameeker
ID:
227036
Filename:
Flumazenil
Updated:
2013-07-14 11:07:22
Tags:
Flumazenil Anexate Romazicon Benzodiazepine Benzo Antagonist paramedic drug study
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Description:
Flumazenil Romazicon Benzo Antagonist
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  1. Flumazenil

    Names / Class
    • Anexate
    • Romazicon

    Benzodiazepine Antagonist
  2. Flumazenil / Romazicon

    Class
    Benzodiazepine Antagonist
  3. Flumazenil / Romazicon

    Mechanism of Action
    Reverses sedative effects of benzodiazepines by inhibiting their actions of GABA
  4. Flumazenil / Romazicon

    Onset of Action
    Peak Effects
    Duration
    Half-Life
    • 1 - 5 minutes
    • 6 - 10 minutes
    • 2 - 4 hours
    • 54 minutes
  5. Flumazenil / Romazicon

    Indications
    To reverse CNS depression associated with benzodiazepine overdose (valium, versed, Ativan, klonopin, Xanax, etc)
  6. Flumazenil / Romazicon

    Contraindications
    • Known hypersensitivity to the med or to benzodiazepines.
    • Pts who received benzos to control life-threatening conditions such as status epilepticus.
    • Tricyclic antidepressant OD.
  7. Flumazenil / Romazicon

    Precautions
    • Don't use as part of a "coma cocktail"
    • Caution in Pts dependent on benzos
  8. Flumazenil / Romazicon

    Side Effects
    • Fatigue
    • HA
    • Agitation
    • Nervousness
    • Dizziness
    • Flushing
    • Confusion
    • Convulsion
    • Arrhythmias
    • Nausea
    • Vomiting
  9. Flumazenil / Romazicon

    Adult Dose
    • 0.2 mg IV over 30 seconds
    • Another 0.3 mg IV can be given over 30 seconds if desired LOC isn't reached within 30 seconds with 1st dose.
    • Further doses of 0.5 mg IV can be given every 1 minute to max of 3 mg.
  10. Flumazenil / Romazicon

    Pedi Dose
    0.01 mg/kg over 30 seconds repeated as needed to max of 1 mg
  11. Flumazenil / Romazicon

    Max Dose
    3 mg
  12. Flumazenil / Romazicon

    Route / How Supplied
    IV

    Vial

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