Intro Ch 1.txt

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Author:
rincrocci
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227342
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Intro Ch 1.txt
Updated:
2013-07-17 00:22:59
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  1. What is the cytoskeleton and what is its' importance in the cell?
    • Composed of a network of proteins and tubules within the cell cytoplasm: 1. Actin filaments (microfilaments) 2. Microtubules and 3. Intermediate filaments
    • Importance: movement of proein from ER to Golgi via microtubules, intercellular motility, role in cell division, protein structure and shape
  2. What types of cellular/intracellular motility are dependent on the actin (microfilament) cytoskeleton?
    • Cell motility, assembly and disassembly in the following:
    • 1. Brush border of epithelial cells: surface expansion
    • 2. epidermis of plants: to allow cytoplasmic flow
    • 3. RBC membrane: form a structural matrix network for stability
    • 4. Bacteria: DNA molecule segregation and cell shape maintenance
    • 5. Slime mold (Physarum): cytoplasmic streaming
  3. What types of cellular/intracellular motility are dependent on the microtubule (MT) cytoskeleton?
    • 1.Cell shape & Maintenance
    • 2.Intracellular transport: dyneins and kinesins which transport vesicles ie:mitochondria
    • 3.Cell wall synthesis in plants
    • 4.Mitotic spindle creation
    • 5.Axoneme in cilia and flagella
  4. What roles do microfilaments (Mfs) play in cell organization/structure/function?
    • 1. Cell motility
    • 2. Intracellular motility
    • 3. Cell Shape
    • 4. Adhesion*
    • 5. Cell-to-cell interactions*
    • 6. Cytokinesis*
    • 7. Cell SIGNALING
  5. What roles do microtubules (Mts) play in cell organization/structure/function?
    • 1. Cell motility
    • 2. Intracellular motility
    • 3. Cell Shape
    • 4. Organization of cytoplasm*
    • 5. Karyokinesis*
    • 6. Cell SIGNALING
  6. What roles do intermediate filaments (Ifs) play in cell organization/structure/function?
    1. Cell and Tissue structure and integrity (and nuclear structure and integrity)

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