- 1. Nontoxic, readily available, BP b/t 50-120 degrees celsius, inexpensive
- 2. BP should be high enough so rapid evaporation isn't a problem, but low enough so that the product can be isolated by rotary evaporation after the fractions are collected.
3. Very non-polar: hydrocarbons, toluene, carbon tetrachloride
4. Slightly polar - diethyl ether, dichloromethane, chloroform (most common)
5. Polar - acetone, ethyl acetate
6. Very polar - ethanol, methanol, water.