4-2

Card Set Information

Author:
ucb160
ID:
227686
Filename:
4-2
Updated:
2013-07-21 21:52:36
Tags:

Folders:

Description:
4-2
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user ucb160 on FreezingBlue Flashcards. What would you like to do?


  1. IV anesthetics
    • barbituates
    • propofol
    • benzodiazepienes
    • etomidate
    • dexmedetomine
    • opiods
  2. What protein is abnormally cleaved in ALD?
    Amyloid pprecursor protein creating senile plaque
  3. Genes associated with ALD
    Amyloid precursor protein(APP)
  4. 4 features of ALD
    • plaques
    • neurofibrillary tangles
    • congophillic amyloid angiopathy(CAA)
    • granulovacular degeneration
  5. neurofibrillary tangles contain what
    tau protein
  6. ALD
    • slowly evolving demntia
    • plaques and amyloid angiopathy contain A4-beta
    • neurofibrillary tangles with tau protein
    • tangles correlate wth Disease
    • death from pnemonia sepsis
  7. Amyotrophic lateral sclerosis
    attacks neurons of brain and voluntary muscles...respiratory failure dies in 3-5 years
  8. ALS gene
    • SOD gene antioxidant functions, excess glutamate. Motor neuron death
    • TDP43 in sporadic cases.

    Intellect intact
  9. Stroke
    Irreversible, mostly infarcts then hemmrrges
  10. TIA
    transient ischemic attack from temporary vascular obstruction
  11. FAST
    Risk factors 70 y/o male, hTN
  12. hemorrhages
    • frm HTN, aneyrysm
    • Can be related to medical conditions, thrombocytopenia, coagulapthy lekemia
  13. giloblastoma
    intraaxial vs eatraaxil(meningioma)
  14. giloblastoma
    pseudopalisading necrosis
  15. meningioma
    • from achradniod cells, benign slow,
    • spradic N2F mutations
  16. meninogoma
    whorls and fibrous collagen
  17. MS
    most common demyelinating diseae, european, waxing and waning of neurologic symptoms, autoimmune
  18. MS symptoms
    • brain shows multiple ovals that are demylinated. Skinny alien fingers, DAwons
    • Shadow plaque
    • CSF has oligoclonal bands
  19. Signs of MS
    • Discrete plaque
    • Dawsons fingers
    • Deyelinated plaques but axons are intact
  20. Dawsons fingers
    • lesion from ventricles
    • demyelinateion is PERIVENOUS
  21. Muscle tension and load are opposing
    tension is force exerted in object
  22. ECM and cytoskeleton of muscle
    collagen matrix, dystrophin complex
  23. Alopecia

    Bulla
    Comedone
    Fomite
    Pruritis
    • hari loss
    • raised lesion greater than 0.5 cm, no ous
    • plug of dead skin matterial at hair follicle
    • inanimate object that can carry disease
    • itching
  24. macule
    • change iin skin color( 1 cm or less)
    • cafe-au-lait
  25. Papule
    elevated, 0.5cm in diameter or less, no depth
  26. nodule
    papule with depth(big n ugly)
  27. vesicle
    small fluid filled lesions
  28. bulla
    blister larger than 0.5 cm
  29. urticaria
    hives, leakage of bld plasma, allergic reactions
  30. plaque
    psoriasis
  31. skin exam
    scalp, nails, exposed skin
  32. hair cycle
    • anagen active phase
    • catagen shirt transitional stage (end of anagen)
    • telogen-resting phase
  33. male pattern baldness
    M pattern, crown bald patch eventually meeting the horseshow shape
  34. how is musclemcontraction regulated?
    alloesterically via calcium
  35. force of contraction is related to chwat?
    calcium
  36. Action potential
    muscle action potential goes down the transverse tubule. SR released calcium. Cacium bined to troponin to remove tropomyosin.
  37. NMJ
    Ca2+ enters voltage gated channels as AP reaches junction ACH re;e;ease.
  38. what is latent period?
    tiem of action potential before muscle contractio happens
  39. SR
    SR, transverse tubules
  40. What triggers CA2+ release from SR?
    DHP recepto binds to Ryanodine
  41. Skeletal EC coupling events
    • 1. AP
    • 2. T tubule polarization
    • 3. DHP receptor
    • 4. Calcium release
    • 5. Calcium bind to troponin C
    • 6. cross bridge cyclling
    • 7. calcium reseuesteration
    • 8. relax
  42. Treatment of Epilepsy
    • medication
    • vagal nerve stimulation
    • ketogenic diet
  43. Seizure risk factors
    • history of seizures
    • stress
    • medications (confirm anti-seizure medications
    • limit stress
    • serum drug levels
  44. Ictal phase
    • tonic -clonic
    • genetly restrain the patient
  45. When to phone 911
    • first time seizure
    • happened in water
    • lasts more than 5 minutes
    • second seizures starts
    • consciousness does not return after ictal phse
  46. Stroke risk
    HTN
  47. Stroke treatment
    • medication
    • dental procedures after 6 months
    • stress reduction
    • epinephrine
  48. Stroke recognition
    • cerebral infarct location
    • weakness
    • numbness
    • headache
    • seizure
    • vomiting
    • lloss of consciouness
    • aphasia
  49. stoke position
    sit upright to decrease intracranial pressure
  50. Indirect-acting adrenergic agonist
    Mixed-acting adrenergic agonist
    • amphetamine
    • vs ephedrine
  51. Indirect acting
    MAOI- monoamine oxidase inhibitors to inhibit breakdown via MAOI
  52. CNS stimulants treat
    • ADHD
    • narcolepsy
    • weight loss
  53. ADHD
    • genetic predisposition, inattention, concentration.
    • Predominately inattentive
    • Predominately hyperactive
  54. ADHD comorbidites
    learning disability, anxiety, mood disorders, tourette disorders
  55. ADHD medication
    methylphenidate to block dopamine reuptake, dextroamohtamine to have MAO inhibition
  56. Atomoxetine
    • ADD and ADHD CYP2D6 metabolized and unschedyled to block NE reuptake
    • Blocking dopamine reuptake means more is available at the cleft
  57. clonidine
    alpha-2 agonist to treat insomia, slower onset
  58. Narcolepsy.modafinl
    increases dopamine and NE release
  59. Ephedrine
    mxed acting adrenergic stimulant gentle epinephrine
  60. sympathomimetic stimulants adverse reactions
    • anorexia
    • insomia
    • constipation
    • HTN
    • abuse
    • sudden death
  61. Xanthine
    • caffeine
    • will anatagonize adenosine receptor and phosphodiesterases.

    effects similar to epinephrine
  62. xanthine derivatives
    • asthma
    • copd

    adverse effects: anorexia, cardio stim, insomia, seisures

What would you like to do?

Home > Flashcards > Print Preview