IM: Test 3 (Part II)

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Author:
BrookeNH10
ID:
227950
Filename:
IM: Test 3 (Part II)
Updated:
2013-07-23 15:01:50
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IM
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IM
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  1. Temperature that lasts for >3 weeks with no obvious source despite appropriate investigation
    Fever of unknown origin
  2. 4 categories of potential etiology of FUO
    • Classic
    • Nosocomial
    • Immune Deficient
    • HIV-related
  3. 4 Subgroups of the DD of FUO
    • Infxns
    • Malginancies
    • Autoimmune conditions
    • Miscellaneous
  4. As fever duration increases
    likelihood of infectious etiology decreases
  5. Most common autoimmune diseases that cause FUO
    • Temporal arteritis (#1 cause in elderly)
    • Adult Still's

    Reflects better serologic dx of other rheum diseases
  6. Still's Major criteria
    • Fever > 39C for >1wk
    • Arthralgia > 2 wks
    • Typical rash
    • WBC >10 w/ > 80% segs
  7. Still's Minor Criteria
    • Sore throat
    • LAN +/- splenomegaly
    • Hepatic abnormalities
    • Negative RF and ANA
  8. Still's Diagnosis
    • 5+ criteria
    • 2+ major criteria
    • Exclude: Infxn, malignancy, other rheum diseases
  9. ESR >100 consider
    • Malignancy (lymphoma, myeloma, mets)
    • Infxns (endocarditis)
    • Collagen-vascular: TA, RA
  10. Neutropenic fever
    • Bacteremia <7days
    • Fungal infxns >7days

    Fever usually abates with return of neutrophils

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