Antiplatelet IIb/IIIa inhibitors
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- Tirofiban - IV
- These drugs bind to the IIb/IIIa receptor complex on the platelet
- This prevents binding of endogenous ligands including fibrinogen and vWF
- Resulting in inhibition of platelet aggregation
- Coronary angioplasty
- High-risk patients with acute MI
- Thrombocytopenia (Most serious complication)
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