Card Set Information
Colony stimulating factors
description of drugs?
trying to increase the amount of neutrophils. If they are low, you can't fight infections.
Granulocyte Colony-Stimulating Factor (G-CSF)
Granulocyte-Monocyte Colony-Stimulating Factor (GM-CSF)
kinetics for Pegfilgrastim:
extended elimination half-life
: 40 hrs!
Produced by the addition of a polyethylene glycol (PEG) to filgrastim
Not as readily cleared by the kidneys Due to large size
Adjunct to myelosuppressive chemotherapy
Severe chronic neutropenia
Prevention and treatment of neutropenia in HIV infection
Sickle cell crises
Acute respiratory distress
Splenomegaly or splenic rupture