Card Set Information
Typical Anti-psychotics (12)
Loxapine (Loxitane, Daxolin)
Typical anti-psychotics and risperidone strongly block which receptors?
Blockade of dopamine in cortical and limbic produces?
Reduction in psychotic S/S
Blockade of dopamine in basal ganglia produces?
Which antipsychotic is effective in treating refractory psychotic S/S?
Which anti-psychotic is approved for use in acute bipolar mania and for maintenance tx of bipolar disorder?
Which 2 anti-psychotics are approved for agitation in schizophrenia?
Which atypical anti-psychotics are approved for bipolar disorder?
What neurological SE must be monitored for when taking antipsychotics?
Neuroleptic malignant syndrome (NMS)
Extrapyramidal S/S (EPS)
What must be monitored in pt taking clozapine?
B/c of agranulocytosis
What are common SE of low potency antipsychotics? (4)
Anti-cholinergic SE (dry mouth, constipation, urinary retention, blurred vision)
Reduced seizure threshold
Cardiac SE (QT prolongation - torsade de pointes)
Which atypical anti-psychotic reduces seizure threshold?
Which anti-psychotics are associated with orthostatic hypotension?
Which anti-psychotic is associated with agranulocytosis?
Which anti-psychotics are associated with QT prolongation?
Which anti-psychotics are associated with high rates of weight gain, dyslipidemia, and adult-onset of diabetes? (2)
Which anti-psychotic can cause pigmentary retinopathy and increased prolactin levels at high does?
Which anti-psychotic increases risk of developing cataracts?
Which class of anti-psychotics are considered the 1st line tx for psychotic disorders?
What is the MOA of atypical anti-psychotics?
Dopamine and serotonin blockade of receptors
Which are the traditional high-potency anti-psychotics?
Which are the traditional medium-potency anti-psychotics?
Which are the traditional low-potency anti-psychotics?
What are common SE of high potency anti-psychotics? (3)
Neuroleptic malignant syndrome
What is neuroleptic malignant syndrome?
Uncommon complication of antipsychotic meds that starts w/in days of usage
High fever, muscle rigidity, increased BP and HR
: stop drug and administer dantrolene
What is tardive dyskinesia?
Complication of anti-psychoitc use begins several months after therapy
Characterized by repetitive facial movements
: stop drug, may be irreversible