Histopath

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Author:
minnoak
ID:
229579
Filename:
Histopath
Updated:
2013-08-09 14:44:07
Tags:
Block histology histopathology
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Description:
Im testing
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  1. Blood is made up of?
    • Plasma: 50% ish? guessing
    • buffy coat: very small (white cells and platelet)
    • RBC (hematocrit): 40-48%
  2. Plasma contains?
    What is the meaning of serum?
    • albumen
    • immunoglobulin
    • other globulins
    • clotting factors

    serum is clotted plasma
  3. Hematocrit is made up of?
    What is the red cell count?
    what is MCV?
    • Hematocrit = RBC X MCV
    • MCV: Mean RBC corpuscular volume(80-100fl)
    • Red cell count: 5x10^9/ml
    • White cell?:5x10^6/ml
    • Platelets?:20x white cell count
  4. RBC size?
    average life span?
    Components of RBC?
    • 7-8 microns
    • 120days

    • membrane, cytoplasm, hemoglobin
    • membrane has the ABO and Rh system
  5. Name the types of leukocytes?
    Granulocytes: neutrophils(segmented, polymorphonuclear PMN) basophils, eosinophils

    mononuclear cells: monocytes, lymphocytes
  6. White cell distribution?
    • 60-70% neutro
    • 5-10 monocyte
    • 20-25 lympho
    • 1% baso and eo
  7. About neutrophils
    does it have lobes? What else is special?
    size?
    What about granules?
    • Segmented neutrophils
    • 9-14um
    • 3-5 lobes with nuclear filament briges

    • Primary granules(also secondary granules aka specific too)
    • contains myeloperoxidase among others
    • red-purple color on stain
    • Also keep in mind that neutrophils are in the blood and they are on guard as back up.  They die faster than macrophages
  8. About eosinophils?
    lobes?
    color?
    function?
    • Eosinophils
    • 2-3 lobes, same size as neutro, coarse RED granules
    • Function:
    • anti-parasitic, immune modulatory
  9. Crystalloid bodies
    granules in eosinophils and contain lots of bases
  10. basophils
    • uncommon
    • contains large dark coarse granules

    • function:
    • mediate hypersensitivity

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