Mood Stabilizers

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Author:
sini
ID:
229918
Filename:
Mood Stabilizers
Updated:
2013-08-13 18:05:18
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Mood Stabilizers
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Mood Stabilizers
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  1. Most common mood stabilizers (4)?
    • Lithium
    • Valproate
    • Carbamazepine
    • Lamotrigine
  2. Uses of Lithium (4)
    • Acute mania
    • Long-term maintenance in bipolar disorder
    • Augmentation of antidepressant medications
    • Impuse dyscontrol
    • Decrease suicide
  3. Uses of valproate (4)
    • Acute mania
    • Rapid-cycling bipolar disorder
    • Mixed features bipolar disorder
    • Impuse dyscontrol
  4. Uses of carbamazepine (4)
    • Acute mania
    • Rapid-cycling bipolar disorder
    • Mixed features bipolar disorder
    • Impulse dyscontrol
  5. Lamotrigine (2)
    • Long-term maintenance in bipolar disorder
    • Mixed features bipolar disorder
  6. Lithium targets which NTs? (3)
    • Norepinephrine
    • Serotonin
    • GABA
  7. How is lithium cleared?
    Renally
  8. What should be monitored regularly while on Lithium (2)
    • Thyroid-stimulating hormone
    • Creatinine
  9. What is the MOA of valproate? (3)
    • Increases GABA synthesis
    • Decreases GABA breakdown
    • Enhances its postsynaptic efficacy
  10. Which is more effective for rapid-cycling and mixed variants of bipolar disorder - valproate or lithium?
    Valproate
  11. Where is valproate metabolized?
    Liver
  12. What are serious SE of valproate? (3)
    • Fatal hepatotoxicity
    • Fulminant pancreatitis
    • Agranulocytosis
  13. Is lamotrigine approved for acute treatment of mania?
    No
  14. Is lamotrigine more effective in treating the depressive or manic phase of bipolar I disorder?
    Despressive
  15. What allergic skin rash develops with lamotrigine?
    Stevens-Johnson's syndrome
  16. Serious SE of carbamazepine (3)
    • Agranulocytosis
    • Pancytopenia
    • Aplastic anemia
  17. Gabapentin is a useful adjunct therapy for?
    Anxiolysis in bipolar disorder
  18. Name atypical antipsychotics approved for mood component of bipolar disorder (5)
    • Olanzapine
    • Quetiapine
    • Risperidone
    • Ziprasidone
    • Aripiprazole

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