local-4

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Author:
ucb160
ID:
229942
Filename:
local-4
Updated:
2013-08-13 23:26:34
Tags:
local
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Description:
local
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  1. systemic reactions from LA
    • toxicity from both LA and Vaso
    • syncope
    • allergic
    • methemoglobemia
  2. LA toxicity if given in excessive doses, intravascular manifests as...
    CNS toxicity then CVS
  3. What is the most potent LA and affects CVS?
    Bupivicane
  4. what is the least potent LA?
    atricane has a ester group
  5. What happens when the LA has high concentration in blood but tissue isnt numb?
    LA was injected in blood vessel rather than tissue space.
  6. what happens upon increase in CBF?
    Brain gets more blood and more drugs
  7. What are signs of brain toxicity?
    • patient is sweaty and experiences and adrenaline rush.
    • worst case: seizure or unconscious coma and die

    Facilitatory impulses, and then both are gone
  8. severe CNS toxicity
    • discoloration
    • tremors
    • respiratory depression
    • seizures
  9. low CNS toxicity
    • sedation
    • analegsia
    • antiatthymic
  10. LETAL LA toxicity
    • coma
    • respiratory arrest
    • CVS collapse
  11. which drugs have higher max doses?
    proliocane and articane
  12. when administereing LA to children go by....
    weight
  13. Why is articane not used on children?
    b/c it has higher concentration of solution.
  14. No Brainer Mthod of LA dosage determination:
    0.5 cartridge per 10 Lb
  15. Main causes of LA toxcity (esp in children)
    • intravascular injection
    • inject too fast
    • injected too much

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