What are the main differences between prokaryotes and eukaryotes?
Eukaryotes have a nucleus, histones, and the mRNA is capped, has a polyA tail, and introns. Prokaryotes do not.
Also, prokaryote transcription and translation are coupled and (like eukaryote germ cells) they have a single copy of their DNA (haploid genome). Somatic Eukaryote DNA is diploid.