Miscellaneous Psych Meds

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sini
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230017
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Miscellaneous Psych Meds
Updated:
2013-08-14 17:42:13
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Miscellaneous Psych Meds
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Miscellaneous Psych Meds
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  1. List common psychostimulants used to tx ADHD (4). What is their MOA? SE? (5)
    • dextroamphetamine
    • methylphenidate
    • adderall
    • pemoline
    • Facilitate endogenous NT (monoamine) release
    • Wt loss, tachycardia, insomnia, anxiety, HTN
  2. What is atomoxetine? Uses? SE? (1)
    • selective norepinephrine re-uptake inhibitor 
    • ADHD
    • Increase risk of suicide in children
  3. What drug class is useful in treating neuroleptic-induced parkinsonism? (2)
    • Anti-cholinergics (main tx)
    • Anti-histamine
  4. What is first line-tx for akathisia? (2)
    • beta-blockers
    • lorazepam
  5. What are SE of anti-cholinergics? (5)
    • blurry vision
    • constipation
    • urinary retention
    • sedation
    • delierium**
  6. List psychiatric uses of beta-blockers  (4)
    • Impulsivity
    • Performance anxiety
    • Akathisia
    • Lithium-induced tremor
  7. List SE of beta-blockers (6)
    • bradycardia
    • hypotension
    • asthma exacerbation
    • masked hypoglycemia with DM
    • fatigue 
    • depressed mood
  8. What is the MOA of Naltrexone? Use?
    • Mu opiod antagnoist
    • Prevent EtOH replase
  9. When do you initiate Naltrexone treatment in regards to EtOH? In regards to co-abuse of opiates?
    • After pt has been detoxified
    • at least 1 week after last opiate exposure
  10. What is Acamprosate used for?
    Maintaining abstinence in previously EtOH-dependent individuals - decreases relapse
  11. What is the MOA of Disulfiram (Antabuse)?
    Blocks oxidation of acetaldehyde --> increase in acetaldehyde (toxic reaction occurs w/in 5-10 mins)
  12. What occurs when pt drinks EtOH while on Disulfiram? (6)
    • Flushing
    • Headache
    • N/V
    • Dizziness
    • CP
    • Dyspnea
  13. What is MOA of Buprenorphine? Use?
    • Partial opioid agonist
    • Opioid detox
  14. What is Subutex?
    Oral buprenorphine
  15. What is Suboxone? Why is it useful?
    • Buprenorphine and naloxone
    • Prevents tablets from being used recreational IV injection
  16. What is Buprenex?
    Oral buprenorphine
  17. What is the MOA of Clonidine?
    CNS alpha2 adrenoreceptor agonist --> inhibits release of CNS norepinephrine
  18. Uses of Clonidine? (4)
    • Decrease S/S of opiate w/drawal
    • ADD
    • Tourette's syndrome
    • Impulsive control
  19. What are SE of Clonidine? (3)
    • Sedation
    • Dizziness
    • Hypotension
  20. List cognitive enhancers that function by blocking Achesterase (4)
    • Donepezil (Aricept)
    • Rivastigmine (Exelon)
    • Galantamine (Reminyl)
    • Tacrine (Cognex)
  21. What are SE of tacrine?  (2)
    • Increase in serum transaminases
    • Severe hepatotoxicity
    • Reserved for 2nd-line tx
  22. What is MOA of Memantine? Uses?
    • NMDA antagonist
    • Tx moderate-to-sever Alzheimer's
  23. What are psychiatric uses of T4?
    Adjunct to lithium for rapid cycling bipolar disorder

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