pharm endo 2/3

Card Set Information

Author:
merazar15
ID:
230935
Filename:
pharm endo 2/3
Updated:
2013-08-22 16:15:58
Tags:
somatostatin
Folders:

Description:
somatostatin analogs, growth hormone antagonist, ACTH
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  1. description of drugs:
    modification of somatostain
  2. drugs:
    • Octreotide (Sandostatin)
    • Lanreotide (Somatuline Depot)
    • Vapreotide (Sanvar IR)
  3. indication and kinetics for Octreotide?
    • acromegaly
    • carcinoid
    • VIPoma
    • IV, SC, IM
  4. indication and kinetics for Lanreotide?
    • acromegaly
    • deep SC
  5. indication and kinetics for Vapreotide:
    • esophageal varices
    • upper GI bleeding
    • variceal bleeding
    • IV
  6. CI
    • caution c/ Type 1 diabetes
    •    altered glucose metabolism
    •     (hypoglycemia can result)
  7. indication:
    • variceal bleeding
    • After pancreatic surgery (reduced suppression of pancreatic secretions)
    • severe refractory chemotherapy-induced diarrhea
    • hepatorenal syndrome
    • suppression of hormones or transmitters
  8. what med is used for Severe refractory chemotherapy-induced diarrhea
    Octreotide 100 mcg SC tid
  9. SE:
    • Cardiovascular:·        
    •    Sinus bradycardia
    • GI related: ·        
    •    Abdominal pain·        
    •    Diarrhea- resolves in 24 hrs     
    •    Nausea
    • CNS :·        
    •    Headache·        
    •    Fatigue

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