Alteplase Recombinant

Card Set Information

Author:
dunks406
ID:
23097
Filename:
Alteplase Recombinant
Updated:
2010-06-11 00:10:37
Tags:
Alteplase Recombinant
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Description:
Alteplase Recombinant
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  1. class
    fibrinolyctic
  2. pharmocology and action
    promotes fibrinolysis by forming the active proteolytic enzyme plasmin. plasmin in turn degrades fibrin fibrinogen and the clot
  3. indications
    fribrinolysis in acute MI acute ischemic shock PE events
  4. contraindications
    • internal bleeding
    • AAA
    • ICP
    • hemorrhagic stroke within the past 6months
    • uncontrolled hypertension
  5. precautions ans side effects
    • internal bleeding
    • superficial bleeding
    • hemorrhagic hypertension
  6. dosage
    • MI/CVA
    • 15mg IV followed by 0.75 mg/kg over 30min. max of 50mg then provide 0.5mg/kg over 60mins max of 35mg

    • pulmmonary embolism
    • 100mg IV infusion over 2hrs.

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