Card Set Information
Chapter 3 Cellular Adaptation
Decrease or shrinkage in celluar size
Occurs with early devolpement. ie. thymus
Occurs as a result in decreases in workload, pressure, use, blood supply, nutrition, hormonal stimulation, and nervous stimulation.
Increase in cell size of cells and consequently in the size of the affected organ.
Increase in the number of cells resulting from an increased rate of cell division.
Adaptive mechanism that enables certain organs to regenerate. ie. liver
Occurs in estrogen-dependant organs. ie uterus and breast
abnormal proliferation of normal cells, in response to exessive hormonal stimulation or growth factors on target cells.
abnormal changes in size, shape, and organization of mature cells.
The reversable replacement of one mature cell type by another
The lack of suffcient oxygen, cause of celluar injury
Reduced blood supply
Reperfusion injury results from the generation of highly reactive oxygen intermediates
Occurs when excess ROS overwhelm endogenous antioxidant systems.
Common degenerative change, caused by the shift of extracelluar water into the cells.
Necroptosis or Cellular Death
Sum of cellular changes after local cell death and the process of cellular self-digestion
Occurs in Kidneys, heart, and adrenal glands. Result from hypoxia or severe ischemia.
Ischemic injury to neurons and gial cells in the brain.
Caseous necrosis "Wisconsin necrosis"
Results from M. Tuberculosis; combination of coagulative and liquefactive necrosis. "Clumps of Cheese"
Cellular dissolution cause by powerful enzymes; lipases;
Occur in breast, pancreas, and other ab structures
"Saponification", opaque-chalk white
Results from severe hypoxic injury
blockage of lower leg
Neutrophils invade the site causing liquefactive necrosis
Active process of cellular self destruction
Programed cell death
normal and pathological tissue