autonomic drugs

Card Set Information

Author:
Anonymous
ID:
233171
Filename:
autonomic drugs
Updated:
2013-09-06 02:00:27
Tags:
medicine
Folders:

Description:
medical drugs
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Anonymous on FreezingBlue Flashcards. What would you like to do?


  1. bethanechol
    • muscarinic agonist
    • - ACh analog resistant to degradation by AChE and BChE
    • - used for GI stasis and urinary retention
  2. pilocarpine
    • muscarinic agonist
    • - tertiary amine --> gets into CNS
    • - used in ophthamology to treat glaucoma and sjogren's syndrome
  3. atropine
    • muscarinic antagonist
    • - blocks ACh through competitive inhibition
    • - tertiary amine --> helps with parkinsons
    • - dec salivation and sweating
    • - to treat cholinesterase poisoning, and emergency care for heart
  4. tropicamide
    • muscarinic antagonist
    • - works like atropine but with shorter half life
    • - used for mydriasis (dilate pupil) in eye exam
  5. tolterodine
    • muscarinic antagonist
    • - like atropine but with M3 receptor preference
    • - used to treat urge incontinence by dec urinary tract motility and voiding
  6. tiotropium
    • muscarinic antagonist
    • - like atropine but a quaternary compound
    • - inhaled to help with COPD and asthma (by inc bronchodilation and dec secretions)
  7. physostigmine
    • acetylcholinesterase inhibitor
    • - indirectly increases parasymp effect
    • - reversible by slow hydrolysis
    • - tertiary amine
    • - used for glaucoma acute attacks and to counter poisoning by anti-muscarinic agents
  8. donepezil
    • acetylcholinesterase inhibitor
    • - indirectly inc parasymp effects
    • - reversible competitive antagonist
    • - tertiary amine, longer lasting
    • - used for alzheimers
  9. neostigmine
    • acetylcholinesterase inhibitor
    • - indirectly inc parasym effects
    • - reversible by slow hydrolysis
    • - quaternary amine;┬áselectivity for NMJ action
    • - used for relieving abdominal distension (inc motility and voiding)
  10. sarin
    • acetylcholinesterase inhibitor
    • - indirectly inc parasymp effects
    • - irreversible organophasphate
    • - ex: nerve gas and insecticides

What would you like to do?

Home > Flashcards > Print Preview