Ch 10 Part 1

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Author:
pugsrule915
ID:
233675
Filename:
Ch 10 Part 1
Updated:
2013-09-08 23:13:38
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10 Part
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Description:
Ch 10 Part 1
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  1. Cardinal Signs of Inflammation
    • Rubor
    • Tumor
    • Color
    • Dolor
    • Functio laesa
  2. Phases of inflammatory response
    • Inflammatory response
    • Fibroblastic repair
    • Maturation and remodeling
  3. Goal of inflammatory response
    • Protect
    • Localize
    • Decrease injurious agents
    • Prepare for healing and repair
  4. Rest
    Reduce reinjury
  5. Ice
    Put into hibernation and prevents secondary cell death from getting clogged and allows necessary nutrients in
  6. Compression
    • Reduce area for inflation
    • Allow for blood clot
  7. Elevation
    • Prevent inflammation
    • Move inflammation back to lymphatic system
    • Reduce blood flow for clotting
  8. Histamine
    • From mast cells
    • Vasodilation and change cell permeability allowing swelling
  9. Leukotrienes and prostaglandins
    • Impact margination
    • Increase permeability for diapedesis
    • Facilitate exudate formation and neutrophil entrance to injured site
  10. Cytokines
    Regulate leukocyte and phagocytic activity
  11. Vascular response during inflammatory phase
    • Vasoconstriction then vasodilation
    • - Increase viscosity lead to slow flow
  12. How a clot is formed
    • Platelets stick to exposed collagen
    • Obstructs lymphatic drainage and localizes injury
  13. Scar tissue formation
    • Prothrombin converted to thrombin in presence of thromboplastin
    • Thrombin causes the change of fibrinogen to fibrin
  14. Chronic inflammation
    • Occurs when acute inflammatory response does not eliminate the injuring agent
    • Leukocytes (WBC) change to lymphocytes
    • Leads to necrosis
    • Reason for shift unknown
    • Associated with overuse

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