CLIN PATH hematology

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CLIN PATH hematology
2013-09-08 23:56:29

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  1. Granulocyte maturation series
    Myeloblast > Promyelocyte > Myelocyte > Metamyelocyte > Band Cell > Segmented Cell
  2. In what stage do the granules in the eosinophil and basophil start to differ in the maturation series.
    Myelocytic stage
  3. Erythrocyte maturation series
    Rubriblast > Prorubricyte > Rubricyte > Metarubricyte > Polychromatophil > RBC
  4. When there is a suspected left shift present, what value in the neutrophils is examined?
    Total count (not %)
  5. Characteristics of an immature cell
    • Nucleolus more visible
    • Clear area visible (golgi)
    • Larger size
    • Blue-light blue cytoplasm
  6. Regenerative left shift
    # of immature cells equal to or less than # of mature cells
  7. Degenerative left shift
    # of immature cells exceeds # of mature cells
  8. Why do we not see a left shift in a stress leukogram?
    There are adequate numbers of neutrophils in storage pools to account for the stressor. So the bone marrow does not have to release immature cells
  9. Define anemia
    Decrease in the oxygen carrying capacity of the blood
  10. Describe the apperance of a metamyelocyte
    kidney bean shaped nucleus.
  11. Causes of anemia
    • Blood parasites (babesia, anaplasma)
    • Kidney disease
    • Ulcers
    • Cancers, tumors
    • Radiation
    • Estogen suppresses bone marrow, induced ovulators get severe anemia if not induced to lower estrogen levels
  12. What lab test would be performed to determine if anemia is regenerative or not?
    Reticulocyte count
  13. MCV
    • mean corpuscular volume
    • size of individual RBC (average)
  14. MCHC
    • mean corpuscular hemoglobin concentration
    • average conc of hemoglobin in RBC
  15. MCH
    • mean corpuscular hemoglobin
    • weight of hemoglobin in average RBC
    • determines if hemoglobin is made properly
  16. RDW
    • RBC Distribution Width
    • range of width of RBCs
  17. What can Heinz Bodies be an indicator of?
    denaturization of hemoglobin
  18. T/F  
    Horses do not release immature RBC's
  19. What are the two forms of reticulocytes in the cat?
    • Aggregate (darker, only ones counted)
    • Punctae (clusters starting to disappear due to maturation)
  20. What do spherocytes look like?
    • no central pallor
    • microcytic
    • densely staining hemoglobin
    • Associated with IMHA