255 hypersensitivity

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elevatedsound7
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234019
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255 hypersensitivity
Updated:
2013-09-10 12:42:22
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255 hypersensitivity
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255 hypersensitivity
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  1. types I, II, and III hyprsensitivity reponses are
    • immediated
    • humoral immunity
  2. if you have had an allergy you have a tyoe ... reponse
    • IgE mediated
    • type I
  3. type IV hypersensitivity reactions are
    • delayed
    • cell-mediated
  4. classifications of hypersensitivity reactions are
    • source of antigen
    • time (immediate or delayed)
    • immunological mechanism causing tissue injury
  5. examples of type I hypersensitivity reactions =
    • allergic rhinitis
    • asthma
  6. atopic =
    inherited tendency
  7. explain type I reaction
  8. posion ivy is what hypersensitivity reaction
    type 4
  9. type I hypersensitivity cause what localized skin reaction
    wheal and flare
  10. Atopic reactions
    inherited tendency to become sensitive to environmental allergens
  11. examples of atopic reactions
    • allergic rhinitis
    • asthma
    • atopic dermatitis
    • urticaria
    • angioedema
  12. urticaria =
    hives
  13. angioedema =
    localized skin lesions similar to hives but involving deeper layers of the skin and submucosa
  14. angioedema effects which areas
    • eyelids
    • lips
    • tongue
    • larynx
    • hands and feet
    • GI genitalia
  15. type II hypersensitivity reactions are what
    cytotoxic and cytolytic reactions
  16. examples of type II reactions =
    • hemolytic transfusion reactions
    • Rh incompatibility reactions
  17. Type II reactions are mediated by what IG
    • IgM
    • IgG
  18. why do you have type II reactions
    mistakenly identifies normal cell as foreiign and destroys target cell
  19. what happens in an acute hemolytic reaction
    • agglutination
    • bleeding
    • urine has hemoglobin in it (because as cell dies it releases hemoglobin into the urine and plasma)
  20. reaction to blood most often occurs when
    within first 15 minutes
  21. clinical manifestations of transfusion reaction
    • chills
    • backache
    • headache
    • CP
    • tachypnea
    • tachycardia
    • hypotension
    • hemoglobinuria
    • jaundice
    • dark urine
  22. Delayed hemolytic transfusion reaction =
    reaction occurs more than 24 hours after transfusion by may not occur up to 14 days
  23. delayed hemolytic transfusion reaction symptoms =
    • 24 hours after transfusion
    • fever
    • mild jaundice
    • decreased hemoglobin
  24. why would someone get a febrile transfusion reaction
    due to leukocyte incompatability
  25. TRALI reaction =
    • Transfusion-related acute lung injury reaction
    • reaction between transfused anti-leukocyte antibodies and recipients leukocytes leading to pulomnary inflammation and edema
  26. type III reactions =
    antigens combine with antibodies that are deposited in tissue and small blood vessels

    • ie glomerular nephritis, rhematoid arthritis
    • common site = kidneys, skin , joints, lungs, bllod vessels
  27. which hypersensitivity reactions are mediated by antibodies
    1, II, III
  28. what reaction is mediated by T cells
    IV
  29. contact dermatitis reactions in type
    IV
  30. latex allergy reaction can be which type
    • I and IV
    • if type IV you get contact dermatitis
    • type I = anaphylacsis
  31. foods that have cross sensitivity for a latex allergy
    • bananas
    • kiwis
    • avocados
    • chestnuts
    • potatoes
    • tomatoes
    • grapes
    • hazelnuts
    • peaches
    • apricots
  32. what is greatest risk factor of latex allergy
    multiple exposures to latex
  33. type IV latex allergy is caused by
    chemicals used in the making of latex
  34. typical signs and symptoms of contact dermatitis
    • itching
    • cracking
    • fissuring
    • redness
    • swelling
    • crusting
  35. autoimmune disease =
    immune response against self

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