kinetics formulas

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Author:
coal
ID:
234122
Filename:
kinetics formulas
Updated:
2013-09-10 22:26:01
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kinetics formulas
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kinetics formulas
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  1. dose equivalent
    new dose = amount of current drug reaching circulation/ (F)(S) of new form
  2. loading dose
    • loading dose = Css *VD
    •                          S*F
  3. volume of distribution
    • Vd = dose
    •           C
  4. clearance
    • cl = dose/tau
    •          Css
  5. elimination rate constant
    • Ke = Cl
    •         Vd
    • Ke = ln (C1/C2)
    •               t
  6. half life
    • T 1/2 = 0.693
    •                Ke
    • T 1/2 = (0.693)(Vd)    [L]
    •                  Cl              [L/hr]

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