rapid review 2

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rapid review 2
2013-09-15 14:24:32

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  1. painful, pale, cold fingers/toes is classical presentation of
    Raynaud's phenomenon (vasospasm in extremities)
  2. painless erythematous lesions on palms and soles is classical presentation of
    Janeway lesions (infective endocarditis, septic emboli/microabscesses)
  3. painless jaundice is classical presentation of
    cancer of the pancreatic head obstructing bile duct
  4. palpable purpura on buttocks/legs, joint pain, abd pain (child), hematuria is classical presentation of
    Henoch-Schonelein purpura (IgA vasculitis affecting skin and kidneys)
  5. pancreatic, pituitary, parathyroid tumors is classical presentation of
    MEN I (autosomal dominanat)
  6. periorbital and/or peripheral edema, proteinuria, hypoalbuminemia, hypercholesterolemia is classical presentation of
    nephrotic synd
  7. pink complexion, dyspnea, hyperventilation is classical presentation of
    Pink puffer (emphysema: centriacinar [smoking], panacinar [α1- antitrypsin deficiency])
  8. polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances, hypophosphatemic rickets is classical presentation of
    Fanconi's anemia (proximal tubular reabsorption defect)
  9. positive anterior "drawer's sign" is classical presentation of
    ant cruciate ligament injury
  10. pruritic, purple, polygonal planar papules and plaques (6Ps) is classical presentation of
    lichen planus
  11. ptosis, myosis, anhidrosis is classical presentation of
    Horner's synd (symp chain lesion)
  12. pupil accommodates but doesn't react is classical presentation of
    Argyll-Robertson pupil (neurosyphilis)
  13. rapidly progressive leg weakness that ascends following GI/upper respiratory infection is classical presentation of
    Guillian-Barre synd (acute autoimmune inflammatory demyelinating polyneuropathy)
  14. rash on palms and soles is classical presentation of
    Coxsackie A, secondary syphilis, Rocky mountain spotted fever
  15. recurrent colds, unusual eczema, high serum IgE is classical presentation of
    hyper-IgE synd (Job's synd: neutrophil chemotaxis abnormailty)
  16. red "currant jelly" sputum in alcoholic or diabetic patient is classical presentation of
    Klebsiella pneumoniae
  17. red "currant jelly" stools is classical presentation of
    acute mesenteric ischemia (adults), intussusception (infants)
  18. red, itchy, swollen rash of nipple/areola is classical presentation of
    Paget's disease of the breast (represents underlying neoplasm)
  19. red urine in the morning, fragile RBCs is classical presentation of
    paroxysomal nocturnal hemoglobinuria
  20. renal cell carcinoma (bilateral), hemangioblastomas, angiomatosis, pheochromocytoma is classical presentation of
    von Hippel-Lindau disease (dominant tumor suppressor gene mutation)
  21. resting tremor, rigidity, akinesia, postural instability is classical presentation of
    Parkinson's disease (nigrostriatal dopamine depletion)
  22. retinal hemorrhages with pale centers is classical presentation of
    Roth's spots (bacterial endocarditis)
  23. severe jaundice in neonate is classical presentation of
    Crigler-Najjar synd (congenital unconjugated hyperbilirubinemia)
  24. severe RLQ pain with palpation of LLQ is classical presentation of
    Rovsing's sign (acute appendicitis)
  25. severe RLQ pain with rebound tenderness is classical presentation of
    McBurney's sign (appendicitis)
  26. short stature, inc incidence of tumors/leukemia, aplastic anemia is classical presentation of
    Fanconi's anemia (genetic loss of DNA crosslink repair; often progresses to AML)
  27. single palmar crease is classical presentation of
    simian crease (Down synd)
  28. situs inversus, chronic sinusitis, bronchiectasis, infertility is classical presentation of
    Kartagner's synd (dynein arm defect affecting cilia)
  29. skin hyperpigmentation, hypotension, fatigue is classical presentation of
    • Addison's disease (primary adrenocortical insufficiency causes inc ACTH and Inc α-MSH production)
  30. slow, progressive muscle weakness in boys is classical presentation of
    Becker's muscular dystrophy (X linked missense mutation in dystrophin; less sever than Duchenne's)
  31. small, irregular red spots on buccal/lingual mucosa with blue-white centers is classical presentation of
    Koplik spots (measles; rubeola virus)
  32. smooth, flat, moist, painless white lesions on genitals is classical presentation of
    condylomata lata (secondary syphilis)
  33. splinter hemorrhages in fingernails is classical presentation of
    bacterial endocarditis
  34. "strawberry tongue" is classical presentation of
    scarlet fever, kawasaki disease, toxic shock synd
  35. streak ovaries, congenital heart disease, horse shoe kidney, cystic hygroma at birth, short stature, webbed neck, lymphedema is classical presentation of
    Turner synd (45, XO)
  36. sudden swollen/painful big toe joint, trophi is classical presentation of
    Gout/podagra (hyperuricemia)
  37. swollen gums, mucosal bleeding, poor wound healing, spots on the skin is classical presentation of
    Scurvy (vit C deficiency: can't hydroxylate proline/lysine for collagen syn)
  38. swollen, hard, painful finger joints is classical presentation of
    Osteoarthritis (osteophytes on PIP [Bouchard's nodes], DIP [Heberden's nodes])
  39. systolic ejection murmur (crescendo-decrescendo) is classical presentation of
    Arotic valve stenosis
  40. thyroid and parathyroid tumors, pheochromocytoma is classical presentation of
    MEN 2A (autosomal dominant ret mutation)
  41. thyroid tumors, pheochromocytoma, ganglioneuromatosis is classical presentation of
    MEN 2B (autosomal dominanat ret mutation)
  42. toe extension/fanning upon plantar scrape is classical presentation of
    Babinski sign (UMN lesion)
  43. unilateral facial drooping involving forehead is classical presentation of
    facial nerve (LMN CN VII palsy)
  44. urethritis, conjunctivitis, arthritis in a male is classical presentation of
    reactive arthritis associated with HLA-B27
  45. vascular birthmark (port-wine stain) is classical presentation of
    hemangioma (benign, but associated with struge-weber synd)
  46. vomiting blood following gastroesophageal lacerations is classical presentation of
    Mallory-Weiss synd (alcoholic and bulimic patients)
  47. weight loss, diarrhea, arthritis, fever, adenopathy is classical presentation of
    Whipple's disease (Tropheryma whipplei)
  48. "worst headache of my life" is classical presentation of
    subarachnoid hemorrhage
  49. anticentromere antibodies is classical finding in
    scleroderma (CREST synd)
  50. antidesmoglein (epithelial) antibodies is classical finding in
    pemphigus vulgaris (blistering)
  51. anti-glomerular basement memb antibodies is classical finding in
    Goodpasture's synd (glomerulonephritis and hemoptysis)
  52. antihistone antibodies is classical finding in
    drug induced SLE (hydralazine, isoniazid, phenytoin, procainamide)
  53. anti-IgG antibodies is classical finding in
    rheumatoid arthritis (systemic inflammation, joint pannus, boutonniere deformity)
  54. antimitochondrial antibodies (AMAs) is classical finding in
    primary biliary cirrhosis (female, cholestasis, portal hypertension)
  55. antineutrophil cytoplasmic antibodies (ANCAs)
    vasculitis (c-ANCA: granulomatosis with polyangitis [Wegner']; p-ANCA: microscopic polyangitis, Churg-Strauss synd)
  56. antinuclear antibodies is classical finding in
    SLE (type III hypersensitivity)
  57. antiplatelet antibodies is classical finding in
    idiopathic thrombocytopenic purpura
  58. anti topoisomerase antibodies is classical finding in
    diffuse systemic scleroderma
  59. anti-transglutaminase/anti-gliadin/anti-endomysial antibodies is classical finding in
    celiac disease (diarrhea, distension, weight loss)
  60. "apple core" lesion on the X ray is classical finding in
    colorectal cancer (usually left sided)
  61. Azurophilic peroxidase-positive granular inclusions in granulocytes and myeloblasts is classical finding in
    Auer rods (acute myelogenous leukemia, especially the promeylocytic [M3] type)
  62. Bacitracin response is classical finding in
    • sensitive: Streptococcus pyogenes (group A);
    • resistant: Streptococcus agalactiae (group B)
  63. "bamboo spine" on X ray is classical finding in
    ankylosing spondylitis (chronic inflammatory arthritis: HLA-B27)
  64. basophilic nuclear remnants in RBCs is the classical finding in
    Howell-Jolly bodies (due to spleenectomy or nonfunctional spleen)
  65. basophilic stippling of RBCs is the classical finding in
    lead poisoning or sideroblastic anemia
  66. bloody tap on LP is the classical finding in
    subarachnoid hemorrhage
  67. "boot shaped" heart on X ray is the classical finding in
    tetralogy of Fallot, RVH
  68. branching gram-positive rods with sulfur granules is the classical finding in
    Actinomyces israelii
  69. bronchogenic apical lung tumor on imaging is the classical finding in
    Pancoast tumor (can compress symp ganglion and cause Horner's synd)
  70. "brown" tumor of bone is the classical finding in
    Hyperparathyroidism or osteitis fibrosa cystica (deposited hemosiderin from hemorrhage gives brown colour)