rapid review 3

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theapk200
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234958
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rapid review 3
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2013-09-15 14:27:02
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  1. cardiomegaly with apical atrophy is the classical finding in
    Chaga's disease (Trypanosoma cruzi)
  2. cellular crescents in Bowman's capsule is the classical finding in
    rapidly progressive crescentic glomerulonephritis
  3. chocolate cyst of ovary is the classical finding in
    endometriosis (frequently involves both ovaries)
  4. circular grouping of dark tumor cells surrounding pale neurofibrils is the classical finding in
    Homer-Wright rosettes (neuroblastoma, medulloblastoma, retinoblastoma)
  5. colonies of mucoid Pseudomonas in lungs is the classical finding in
    cystic fibrosis (autosomal recessive mutation in CFTR resulting in fat soluble vitamin deficiency and mucous plugs)
  6. decreased α-feto protein in amniotic fluid/maternal serum is the classical finding in
    Down synd or other chromosomal abnormality
  7. degeneration of dorsal column nerves is the classical finding in
    Tabes dorsalis (tertiary syphilis), subacute combined degeneration (dorsal columns and lateral corticospinal tracts affected)
  8. depigmentation of neurons in substantia niagra is the classical finding in
    Parkinson's disease (basal ganglia disorder: rigidity, resting tremor, bradykinesia)
  9. desquamated epithelium casts in sputum is the classical finding in
    Curschmann's spirals (bronchial asthma;can result in whorled mucous plugs)
  10. disarrayed granulosa cells in eosinophilic fluid is the classical finding in
    Call-Exner bodies (granulosa - theca cell tumor of the ovary)
  11. dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia is the classical finding in
    koilocytes (HPV: predisposes to cervical cancer)
  12. enlarged cells with intranuclear inclusion bodies is the classical finding in
    "owl's eye" appearance in CMV
  13. enlarged thyroid cells with ground glass nuclei is the classical finding in
    "orphan Annie's eyes" nuclei (papillary carcinoma of the thyroid)
  14. eosinophilic cytoplasmic inclusion in the liver cell is the classical finding in
    Mallory bodies (alcoholic liver disease)
  15. eosinophilic cytoplasmic inclusion in nerve cell is the classical finding in
    Lewy body (parkinson's disease)
  16. eosinophilic globule in liver is the classical finding in
    Councilman body (toxic or viral hepatitis, often yellow fever)
  17. eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells is the classical finding in
    Negri bodies of rabies (Lyssavirus)
  18. extracellular amyloid deposition in gray matter of brain is the classical finding in
    Senile plaques (Alzheimer's disease)
  19. Giant B cells with bilobed nuclei with prominent inclusions ("owl's eye") is the classical finding in
    Reed-Sternberg (Hodgkin's lymphoma)
  20. Glomerulus like structure surrounding vessel in germ cells is the classical finding in
    Schiller-Duval bodies (yolk sac tumor)
  21. "hair on end" (crew cut) appearance on Xray is the classical finding in
    β thalassemia, sickle cell anemia (marrow expansion)
  22. hCG elevated is the classical finding in
    Choriocarcinoma, hydatiform mole (occurs with and without embyo)
  23. heart nodules (granulomatous) is the classical finding in
    Aschoff bodies (rheumatic fever)
  24. heterophile antibodies is the classical finding in
    infectious mononucleosis (EBV)
  25. hexagonal, dougle-pointed, needle like crystals in bronchial secretions is the classical finding in
    Bronchial asthma (Charcot-Leyden crystal: eosinophilic granules)
  26. high level of D-dimers is the classical finding in
    DVT, pulmonary embolism, DIC
  27. hilar lymphadenopathy, peripheral grnaulomatous lesion in middle or lower lung lobes (can calcify) is the classical finding in
    Ghon complex (primary TB: mycobacterium bacilli)
  28. "Honeycomb lung" on X ray or CT is the classical finding in
    interstitial pulm fibrosis
  29. hypercoagulability (leading to migrating DVTs and vasculitis) is the classical finding in
    Trousseau's synd (adenocarcinoma of pancreas or lung)
  30. hypersegmented neutrophils is the classical finding in
    megloblastic anemia (B12 deficiency: neurologic symp; folate deficiency: no neurologic symp)
  31. hypertension, hypokalemia, metabolic alkalosis is the classical finding in
    Conn's synd
  32. hypochromic, microcytic anemia is the classical finding in
    Fe deficiency anemia, lead poisoning, thalassemia (fetal Hb sometimes present)
  33. increase alpha fetoprotein in amniotic fluid/maternal serum is the classical finding in
    Dating error, anencephaly, spina bifida (neural tube defects)
  34. increased uric acid levels is the classical finding in
    Gout, Lesch-Nyhan synd, tumor lysis synd, loop and thiazide diuretics
  35. intranuclear eosinophilic droplet like bodies is the classical finding in
    Cowdry type A bodies (HSV or CMV)
  36. Fe containing nodules in alveolar septum is the classical finding in
    Ferruginous bodies (asbestosis: inc chance of mesothelioma)
  37. keratin pearls on a skin biopsy is the classical finding in
    squamous cell carcinoma
  38. large lysosomal vesicles in phagocytes, immunodeficiency is the classical finding in
    Chediak-Higashi disease (congenital failure of phagolysosome formation)
  39. "Lead pipe" appearance of colon on barium enema X ray is the classical finding in
    Ulcerative colitis (loss of hustra)
  40. Linear appearance of IgG depositon on glomerular basement memb is the classical finding in
    Goodpasture's synd
  41. low serum Ceruloplasmin is the classical finding in
    Wilson's disease (hepatolenticular degeneration)
  42. "lumpy bumpy" appearance of glomeruli on immunofluorescence is the classical finding in
    post streptococcal glomerulonephritis (immune complex deposition of IgG and C3b)
  43. Lytic ("hole punched") bone lesions on X ray is the classical finding in
    Multiple myeloma
  44. mammary gland ("blue domed") cyst is the classical finding in
    fibrocystic change of breast
  45. Monoclonal antibody spike is the classical finding in
    • Multiple myeloma (usually IgG or IgA)
    • monoclonal gammopathy of undetermined significance (MGUS; normal consequence of aging)
    • Waldenstrom's (M protein=IgM) macroglobulinemia
    • primary amyloidosis
  46. mucin filled cell with peripheral nucleus is the classical finding in
    Signet ring (gastric carcinoma)
  47. narrowing of bowel lumen on barium X ray is the classical finding in
    "String sign" (Crohn's disease)
  48. necrotising vasculitis (lungs) and necrotising glomerulonephritis is the classical finding in
    Granulomatosis with polyangitis (Wegner's; c-ANCA positive) and Goodpasture's synd (anti-basement memb antibodies)
  49. needle shaped, negative birefringent crystals is the classical finding in
    Gout (monosodium urate crystals)
  50. nodular hyaline deposits in glomeruli is the classical finding in
    Kimmelstiel-Wilson nodules (diabetic nephropathy)
  51. Novobiocin response is the classical finding in
    • sensitive: Staphylococcus epidermidis;
    • resistant: Staphylococcus saprophyticus
  52. "Nutmeg" appearance of liver is the classical finding in
    chronic passive congestion of liver due to right heart failure
  53. "Onion skin" periosteal reaction is the classical finding in
    Ewing's sarcoma (malignant round cell tumor)
  54. Optochin response is the classical finding in
    • sensitive: Streptococcus pneumoniae
    • resistant: Viridans streptococcus
  55. periosteum raised from bone, creating triangular area is the classical finding in
    Codman's triangle on X ray (osteosarcoma, Ewing's sarcoma, pyogenic osteomyelitis)
  56. podocyte fusion or "effacement" on electron microscopy is the classical finding in
    Minimal change disease (child with nephrotic synd)
  57. Polished, "ivory like" appearance of bone at cartilage erosion is the classical finding in
    Eburnation (osteoarthritis resulting in bony sclerosis)
  58. protein aggregates in neurons due to hyperphosphorylation of protein tau is the classical finding in
    Neurofibrillary tangles (Alzheimer's disease) and Pick's bidies (Pick's disease)
  59. psammoma bodies is the classical finding in
    meningiomas, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of endometrium and ovary
  60. Pseudopalisading cells on brain biopsy is the classical finding in
    Glioblastoma multiforme
  61. RBC casts in urine is the classical finding in
    Acute glomerulonephritis
  62. rectangular, crystal like, cytoplasmic inclusions in Leydig cells is the classical finding in
    Reinke crystals (Leydig cell tumor)
  63. renal epithelial casts in urine is the classical finding in
    Acute toxic/viral nephrosis
  64. rhomboid crystals, positively birefringent is the classical finding in
    Pseudogout (calcium pyrophosphate dihydrate crystals)
  65. rib notching is the classical finding in
    coarctation of aorta
  66. ring enhancing brain lesion in AIDS is the classical finding in
    Toxoplasma gondii, CNS lymphoma
  67. sheets of medium sized lymphoid cells with scattered pale, tingible body-laden macrophages ("starry sky" histology) is the classical finding in
    Burkitt's lymphoma (t[8:14] c-myc activation, associated with EBV; "black sky" made up of malignant cells)
  68. silver staining spherical aggregation of tau proteins in neurons is the classical finding in
    Pick's bodies (Pick's disease: progressive dementia, changes in personality)
  69. "soap bubble" in femur or tibia on X ray is the classical finding in
    Giant cell tumor of bone (generally benign)
  70. "spikes" on basement memb, "dome like" subepithelial deposits is the classical finding in
    membranous glomerulonephritis (may progress to nephrotic synd)

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